24 HOUR MANOMETRIC RECORDING OF COLONIC MOTOR-ACTIVITY IN HEALTHY MAN
24 HOUR MANOMETRIC RECORDING OF COLONIC MOTOR-ACTIVITY IN HEALTHY MAN
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DOI：
10.1136/gut.28.1.17
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发表时间：
1987-01-01
期刊：
影响因子：
24.5
通讯作者：
MORELLI, A
中科院分区：
文献类型：
--
作者：
NARDUCCI, F;BASSOTTI, G;MORELLI, A
使用结肠镜定位导管对 14 名健康志愿者进行 24 小时的横结肠、降结肠和乙状结肠的运动活动记录。在研究期间，患者吃了两顿 1000 kcal 的混合餐和一份欧陆式早餐。结肠运动活动在饭前较低，在睡眠期间也很少；饭后和早晨醒来时运动指数显着增加。大多数运动活动表现为单独或突发的低幅度收缩，没有显示出可识别的模式。除两名受试者外，所有受试者均表现出孤立的高振幅（高达 200 毫米汞柱）收缩，并以约 1 厘米/秒的速度长距离蠕动传播。大多数宫缩发生在早晨醒来后，也有一些发生在餐后后期，平均为 4.4 次/受试者/24 小时。蠕动收缩通常被认为是排便的冲动或排便前的感觉，并且可以代表质量运动的测压等效值。
The motor activity of the transverse, descending, and sigmoid colon was recorded for 24 hours in 14 healthy volunteers with a colonoscope positioned catheter. During the study the patients ate two 1000 kcal mixed meals and one continental breakfast. Colonic motor activity was low before meals and minimal during sleep; the motility index increased significantly after meals and at morning awakening. Most of the motor activity was represented by low amplitude contractions present singly or in bursts, which showed no recognisable pattern. All but two subjects also showed isolated high amplitude (up to 200 mmHg) contractions that propagated peristaltically over long distances at approximately 1 cm/sec. Most of these contractions occurred after morning awakening, and some in the late postprandial period, with a mean of 4.4/subject/24 h. The peristaltic contractions were often felt as an urge to defecate or preceded defecation, and could represent the manometric equivalent of the mass movements.