Various imaging modalities for the detection of salivary gland lesions:: The advantages of 201Tl SPET
Various imaging modalities for the detection of salivary gland lesions:: The advantages of 201Tl SPET
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DOI：
10.1097/00006231-200003000-00012
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发表时间：
2000-03-01
影响因子：
1.5
通讯作者：
Araki, T
中科院分区：
文献类型：
--
作者：
Arbab, AS;Koizumi, K;Araki, T
本研究的目的是比较双同位素（Tc-99(m)和Tl-201） SPET成像与计算机断层扫描（CT）和磁共振成像（MRI）对大唾液腺各种病变的鉴别价值。22例患者接受了双同位素SPET成像，其中12例同时进行了CT检查，15例同时进行了MRI检查。通过在受累腺体和正常腺体上绘制感兴趣区域，计算Tc-99和Tl-201的摄取比和保留指数(m)。CT和MRI均由两名放射科医生进行解释。所有恶性肿瘤均通过三种方式检测到。采用双同位素SPET成像检测Warthin肿瘤；然而，MRI未能区分Warthin瘤与多形性腺瘤。在其他13个良性肿瘤中，双同位素SPET正确诊断了12个。在Tc-99(m)图像上显示冷缺陷的16个肿瘤中，Tl-201参数分析的准确率为94%，而CT的准确率为70-90%。MRI鉴别良性（沃辛氏）和恶性肿瘤的准确率为73-91%。我们认为，双同位素SPET成像（Tc-99(m)和Tl-201）以及半定量分析是鉴别主要唾液腺各种病变的首选方法。(C) 2000 Lippincott Williams & Wilkins)。
The aim of this study was to compare dual-isotope (Tc-99(m) and Tl-201) SPET imaging with computed tomography (CT) and magnetic resonance imaging (MRI) in the differentiation of various lesions of the major salivary glands. Twenty-two patients underwent dual-isotope SPET imaging, of whom 12 also had CT and 15 also had an MRI study. The uptake ratio and retention index for Tc-99(m) and Tl-201 were calculated by drawing regions of interest on the involved and normal glands. Both CT and MRI were interpreted by two radiologists. All malignant tumours were detected by all three modalities. Warthin's tumours were detected by dual-isotope SPET imaging; however, MRI failed to differentiate Warthin's tumour from pleomorphic adenoma. Of 13 other benign tumours, dual-isotope SPET correctly diagnosed 12. Of 16 tumours showing a cold defect on the Tc-99(m) images, parametric analysis with Tl-201 gave an accuracy of 94%, whereas CT gave an accuracy of 70-90%. MRI was 73-91% accurate in differentiating between benign (Warthin's) and malignant tumours. We believe that dual-isotope SPET imaging (Tc-99(m) and Tl-201), together with semi-quantitative analysis, is the method of choice for differentiating between various lesions of the major salivary glands. ((C) 2000 Lippincott Williams & Wilkins).