Pyridine Derivatives as Insecticides. Part 1: Synthesis and Toxicity of Some Pyridine Derivatives Against Cowpea Aphid, Aphis craccivora Koch (Homoptera: Aphididae)
Pyridine Derivatives as Insecticides. Part 1: Synthesis and Toxicity of Some Pyridine Derivatives Against Cowpea Aphid, Aphis craccivora Koch (Homoptera: Aphididae)
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DOI：
10.1021/jf503992y
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发表时间：
2014-10-15
影响因子：
6.1
通讯作者：
Abdel-Raheem, Shaban A. A.
中科院分区：
文献类型：
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作者：
Bakhite, Etify A.;Abd-Ella, Aly A.;Abdel-Raheem, Shaban A. A.
5个吡啶衍生物，即N-吗啉鎓 7，7-二甲基-3-氰基-4-（4'-nitrophenyl）-5-oxo-1，4，5，6，7，8-hexahydroquinoline-2-thiolate（1），sodium 5-acetyl-3-amino-4-（4 ′-甲氧基苯基）-6-甲基噻吩并[2，3-B]吡啶-2-甲酸酯（2），3，5-二氰基-2-氧代-4-螺环戊烷-1，2，3，制备纯态的4-四氢吡啶-6-硫醇盐（3）、哌啶鎓 5-乙酰基-3-氰基-4-（4 ′-甲氧基苯基）-6-甲基-吡啶-2-硫醇盐（4）和哌啶鎓 5-乙酰基-4-（4 ′-氯苯基）-3-氰基-6-甲基-吡啶-2-硫醇盐（5），并进行标题研究。生物活性测定结果表明，化合物1的杀虫活性约为啶虫脒的4倍。其余化合物具有中等至较强的杀蚜活性。
Five pyridine derivatives, namely, N-morpholinium 7,7-dimethyl-3-cyano-4-(4'-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-2-thiolate (1), sodium 5-acetyl-3-amino-4-(4'-methoxyphenyl)-6-methylthieno[2,3-b] pyridine-2-carboxylate (2), piperidinium 3,5-dicyano-2-oxo-4-spirocyclopentane-1,2,3,4-tetrahydropyridine-6-thiolate (3), piperidinium 5-acetyl-3-cyano-4-(4'-methoxyphenyl)-6-methylpyridine-2-thiolate (4), and piperidinium 5-acetyl-4-(4'-chlorophenyl)-3-cyano-6-methyl-pyridine-2-thiolate (5) were prepared in pure state and subjected to the title study. The bioassay results indicated that the insecticidal activity of compound 1 is about 4-fold that of acetamiprid insecticide. The rest of the tested compounds possess moderate to strong aphidicidal activities.