Silicosis and silicotuberculosis among respiratory hospital admissions: A cross-sectional survey in northern Tanzania.
Silicosis and silicotuberculosis among respiratory hospital admissions: A cross-sectional survey in northern Tanzania.
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DOI：
10.7196/ajtccm.2023.v29i3.269
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发表时间：
2023
影响因子：
--
通讯作者：
Nyakunga G
中科院分区：
文献类型：
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作者：
Dennis E;Mussa H;Sanga MP;Howlett P;Nyakunga G
几乎没有证据表明全世界4 050万小规模矿工患有呼吸道疾病。 描述坦桑尼亚一家三级医院中患有矽肺和矽肺结核的成人呼吸系统住院患者的患病率和临床特征。 在这项回顾性横断面调查中，从2010年至2020年的入院患者档案中随机选择并纳入呼吸系统诊断。 在223例呼吸系统疾病患者中，32例（14.3%; 95%置信区间（CI）10.0 - 19.6）被诊断为矽肺，17例（7.6%; 95% CI 4.5 - 11.9）被诊断为矽肺结核。在矽肺（n=15/32; 46.9%）和矽肺结核（n=15/17; 88.2%）患者中，采矿是最常见的职业。在矽肺或矽肺结核患者中，26/49例（53.1%）年龄<45岁。 我们的研究表明，矽肺和矽肺结核是常见的男性和女性呼吸道住院病人的职业暴露。该研究强调了职业暴露在发展中经济体呼吸系统疾病中的作用。 该研究补充说。这项回顾性横断面调查描述了坦桑尼亚北方三级医院收治的成人呼吸系统住院患者中矽肺和矽肺结核的患病率。这是第一项描述非洲小规模矿区呼吸系统住院矽肺和矽肺结核病患者患病率和特征的研究。矽肺（14.3%）和矽肺结核（7.6%）的患病率较高，患者年龄多在45岁以下，大多数需要氧疗。调查结果的影响。晚期矽肺和矽肺结核在年轻矿工中的高患病率引起了人们对高职业二氧化硅暴露的担忧，重要的是，这表明需要进行基于社区的研究，我们的团队正计划进行这项研究。
There is little evidence describing respiratory disease among 40.5 million small-scale miners worldwide. To describe the prevalence and clinical characteristics of adult respiratory inpatients with silicosis and silicotuberculosis in a tertiary hospital in Tanzania that serves a small-scale mining region. In this retrospective, cross-sectional survey, patient files from admissions between 2010 and 2020 were opportunistically selected and included if a respiratory diagnosis had been made. Of 223 patients with respiratory conditions, 32 (14.3%; 95% confidence interval (CI) 10.0 - 19.6) were diagnosed with silicosis and 17 (7.6%; 95% CI 4.5 - 11.9) with silicotuberculosis. Mining was the most frequent occupation in those with silicosis (n=15/32; 46.9%) and silicotuberculosis (n=15/17; 88.2%). Of those with silicosis or silicotuberculosis, 26/49 (53.1%) were aged <45 years. Our study suggests that silicosis and silicotuberculosis are common among male and female respiratory inpatients with occupational exposure. The study highlights the role of occupational exposures in respiratory disease in developing economies. What the study adds. This retrospective, cross-sectional survey describes the prevalence of silicosis and silicotuberculosis among adult respiratory inpatients admitted to a tertiary hospital in northern Tanzania. It is the first study to describe the prevalence and characteristics of respiratory inpatients with silicosis and silicotuberculosis in a small-scale mining region of Africa. A high prevalence of silicosis (14.3%) and silicotuberculosis (7.6%) was found. Patients were often aged <45 years, and the majority required oxygen therapy. Implications of the findings. The high prevalence of advanced silicosis and silicotuberculosis in miners presenting at a young age raises concerns about high occupational silica exposures and, importantly, suggests a need for community-based research, which our team is planning to undertake.