Genealogical process on a correlated fitness landscape.
Genealogical process on a correlated fitness landscape.
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相关健身景观的谱系过程。
DOI：
10.1002/jez.10146
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
J. Fontanari
中科院分区：
文献类型：
--
作者：
C. Wilke;P. Campos;J. Fontanari
我们研究了广泛的数值模拟的系谱过程中的2N单倍体遗传序列。这些序列处于选择压力下，并且适应度值是随机分配的，但是与密切相关的序列的适应度值具有可调的相关度。我们观察到的系谱可以分为三个不同的类别，对应于不同的突变率制度。在低突变率下，序列仍然定位在少数中心序列周围，这导致树的成对距离较短，并且种群最近的共同祖先更替缓慢。在高突变率下，我们观察到与中性进化相似（但不相同）的树。在这种制度下，人口迅速漂移，选择不影响人口中的适应值的分布。第三个政权，中间突变率，只发现在强相关的景观。它类似于高突变率的群体迅速漂移，但选择仍然塑造了适应值的分布。
We study with extensive numerical simulation the genealogical process of 2N haploid genetic sequences. The sequences are under selective pressure, and fitness values are assigned at random, but with a tunable degree of correlation to the fitness values of closely related sequences. The genealogies that we observe can be classified into three different categories, corresponding to different regimes of the mutation rate. At low mutation rates, the sequences remain localized around a small number of central sequences, which leads to trees with short pairwise distances and slow turnover of the most recent common ancestor of the population. At high mutation rates, we observe trees similar (but not identical) to those of neutral evolution. In this regime, the population drifts rapidly, and selection does not influence the distribution of fitness values in the population. The third regime, for intermediate mutation rates, is only found in strongly correlated landscapes. It resembles the one for high mutation rates in that the population drifts rapidly, but nevertheless selection still shapes the distribution of fitness values.