Greater temperature variation within a day associated with increased emergency hospital admissions for asthma
Greater temperature variation within a day associated with increased emergency hospital admissions for asthma
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DOI：
10.1016/j.scitotenv.2014.10.003
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发表时间：
2015-02-01
影响因子：
9.8
通讯作者：
Tian, Linwei
中科院分区：
文献类型：
--
作者：
Qiu, Hong;Yu, Ignatius Tak-sun;Tian, Linwei
哮喘是儿童和成人最常见的慢性疾病之一。检查温度变化等环境触发因素对健康的影响可能对哮喘控制和预防的维持有意义。我们假设较大的昼夜温度范围（DTR）可能是额外环境压力的来源，因此是哮喘恶化的危险因素。收集了2004年至2011年香港的每日气象数据、空气污染浓度和哮喘急诊住院人数。在调整了时间趋势、季节性、平均温度、湿度和室外空气污染水平后，使用泊松回归模型拟合每日DTR与哮喘之间的关系。观察DTR对哮喘的急性不良反应。在第0天至第4天，DTR升高1摄氏度与每日哮喘急诊住院人数增加2.49% （95% CI: 1.86%, 3.14%）相关。在每日绝对温度和空气污染的调节下，DTR和哮喘之间的相关性很强。DTR在凉爽季节表现出显著的效果。男性和女性儿童似乎更容易受到DTR的影响。结果支持一天内较大的温度变化是哮喘恶化的环境危险因素。(C) 2014 Elsevier B.V.版权所有
Asthma is one of the most common chronic conditions affecting both children and adults. Examining the health effects of environmental triggers such as temperature variation may have implications for maintenance of asthma control and prevention. We hypothesized that large diurnal temperature range (DTR) might be a source of additional environmental stress and therefore a risk factor for asthma exacerbation. Daily meteorological data, air pollution concentrations and emergency hospital admissions for asthma from 2004 to 2011 in Hong Kong were collected. Poisson regression models were used to fit the relationship between daily DTR and asthma, after adjusting for the time trend, seasonality, mean temperature, humidity, and levels of outdoor air pollution. Acute adverse effect of DTR on asthma was observed. An increment of 1 degrees C in DTR over lag0 to lag4 days was associated with a 2.49% (95% CI: 1.86%, 3.14%) increase in daily emergency asthma hospitalizations. The association between DTR and asthma was robust on the adjustment for daily absolute temperature and air pollution. DTR exhibited significantly greater effect in cool season. Males and female children appeared to be more vulnerable to DTR. Results supported that greater temperature variation within a day was an environmental risk factor for asthma exacerbation. (C) 2014 Elsevier B.V. All rights reserved.