Pediatric multiple sclerosis:: Detection of clinically silent lesions by multimodal evoked potentials
Pediatric multiple sclerosis:: Detection of clinically silent lesions by multimodal evoked potentials
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DOI：
10.1016/j.jpeds.2006.01.003
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发表时间：
2006-07-01
影响因子：
5.1
通讯作者：
Hanefeld, Folker
中科院分区：
文献类型：
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作者：
Pohl, Daniela;Rostasy, Kevin;Hanefeld, Folker
儿童多发性硬化症(MS)患者由于缺乏空间播散的证据，经常不符合MRI的诊断标准。我们评估了多模式诱发电位(EP)的诊断价值。在85例儿童多发性硬化症患者中，46%的患者在第二次临床发作前通过诱发电位检测到空间播散。EP可作为儿科MS早期诊断的重要手段。
Pediatric patients with multiple sclerosis (MS) frequently do not meet MRI criteria for diagnosis because of lack of evidence of dissemination in space. We assessed the diagnostic utility of multimodal evoked potentials (EP). In 46% of 85 childhood patients with MS, spatial dissemination was detected by EP before the second clinical attack. EP may constitute an important tool for earlier diagnosis of pediatric MS.