Validity of visual perceptive computing for static posturography in patients with multiple sclerosis
Validity of visual perceptive computing for static posturography in patients with multiple sclerosis
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DOI：
10.1177/1352458515625807
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发表时间：
2016-10-01
影响因子：
5.8
通讯作者：
Schmitz-Huebsch, Tanja
中科院分区：
文献类型：
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作者：
Behrens, Janina R.;Mertens, Sebastian;Schmitz-Huebsch, Tanja
背景：多发性硬化症（MS）患者经常有姿势控制障碍，但在临床护理中难以进行定量姿势照相。最近的技术促进了新的姿势学方法。目的：评价视觉感知计算（VPC）静态体位测量的构念效度，以研究多发性硬化症患者的体位控制。方法：90例MS患者和59例健康对照（hc）进行了三种站立试验：开放、封闭和串联站立。使用带有Microsoft Kinect的VPC系统进行静态姿势照相。临床评估包括扩展残疾状态量表（EDSS）、计时-25英尺步行、短-最大速度步行和12项MS步行量表（MSWS-12）问卷。重测时用类内相关系数评估信度。结果：作为一个整体，MS患者在所有测试中的表现都比hc患者差。闭式试验结果表明，该方法具有较好的适用性和可靠性。闭眼时，36.7%的患者三维平均角摇摆速度（MSV-3D）高于hcc的第95百分位。较高的MSV-3D与行走速度降低相关（p < 0.001）；临床评分较差，主要归因于小脑功能系统评分（p < 0.001）；并反映在自我报告的行走障碍中（MSWS-12, p < 0.001）。结论：基于vpc的静态体位摄影可以可靠地评估ms患者的姿势控制，异常的姿势控制似乎主要反映了小脑回路的参与，对步态和行走障碍有影响。
Background: Multiple sclerosis (MS) patients frequently have postural control impairment but quantitative posturography is difficult to perform in clinical care. Recent technology facilitates new posturography approaches.Objective: To evaluate construct validity of visual perceptive computing (VPC) for static posturography to study postural control in MS patients.Methods: A total of 90 MS patients and 59 healthy controls (HCs) performed three stance tests: open, closed and tandem stance. Static posturography was performed using a VPC system with Microsoft Kinect. Clinical assessments included Expanded Disability Status Scale (EDSS), Timed-25-Foot-Walk, Short-Maximum-Speed-Walk and 12-item MS Walking Scale (MSWS-12) questionnaire. Reliability was assessed with intra-class correlation coefficients at retest.Results: As a group, MS patients performed worse than HCs in all tests. The closed stance test showed best applicability and reliability. With closed eyes, in 36.7% of patients, the three-dimensional mean angular sway velocity (MSV-3D) was above HCs' 95th percentile. Higher MSV-3D was associated with decreased walking speed (p < 0.001); worse clinical scores, mainly attributable to the cerebellar functional system score (p < 0.001); and reflected in self-reported walking disability (MSWS-12, p < 0.001).Conclusion: Postural control can be reliably assessed by VPC-based static posturography in patients with MS. Abnormal postural control seems to predominantly reflect involvement of cerebellar circuits with impact on gait and walking disability.