Initial experience with radiofrequency ablation for hepatic tumours in the Netherlands
Initial experience with radiofrequency ablation for hepatic tumours in the Netherlands
复制标题
DOI：
10.1016/s0748-7983(03)00146-x
复制
发表时间：
2003-11-01
期刊：
影响因子：
--
通讯作者：
Van Gulik, TM
中科院分区：
文献类型：
--
作者：
Mutsaerts, ELAR;Van Coevorden, F;Van Gulik, TM
目的：本研究的目的是报告的初步经验与射频热消融（RFA）的恶性肝tumors.Methods：从1999年6月至2001年11月，一个7个中心的研究50例谁经历了RFA，包括102原发性或转移性肿瘤。记录多模式治疗、并发症、无病生存率和复发位置。组织学检查进行了一些肿瘤与RFA治疗，随后切除，以确定RFA对组织level.Results的效果：11个肿瘤（7例）切除后，与RFA治疗前，在所有这些肿瘤的NADH-黄递酶染色证明非可行的肿瘤。在与RFA手术相关的3例病例中，分别有14例患者和1例患者发生术后发病和死亡。41例未切除射频消融肿瘤患者的中位随访时间为11个月（范围1 - 24个月）。26例患者复发，其中三个在RFA网站后6-12 months.Conclusions：RFA提供了一种简单的方法，局部治疗肝脏肿瘤。然而，这项技术的引入涉及发病率和死亡率。(C)2003年由Elsevier Ltd.出版
Aims: The aim of this study is to report initial experience with radiofrequency thermoablation (RFA) of malignant hepatic tumours.Methods: From June 1999 to November 2001, a seven centre study of 50 patients who had undergone RFA, included 102 primary or metastatic tumours. Multimodality therapy, complications, disease free survival and location of recurrence were recorded. Histopathologic examination was performed in a number of tumours treated with RFA and subsequently resected to determine the effect of RFA on the tissue level.Results: 11 tumours (seven patients) were resected after prior treatment with RFA; NADH-diaphorase staining in all these tumours demonstrated non-viable tumour. Postoperative morbidity and mortality occurred in 14 patients and one patient, respectively, in three cases related to the RFA procedure. Median follow-up of 41 patients with non-resected RF ablated tumours was 11 months (range 1 -24 months). 26 patients developed a recurrence of which three at the RFA site after 6-12 months.Conclusions: RFA provides a simple method for local treatment of liver tumours. The introduction of this technique nevertheless involves morbidity and mortality. (C) 2003 Published by Elsevier Ltd.