Inter- and intra-population genetic divergence of East Asian cattle populations: focusing on Korean cattle
Inter- and intra-population genetic divergence of East Asian cattle populations: focusing on Korean cattle
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DOI：
10.1007/s13258-013-0146-9
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发表时间：
2014-06-01
期刊：
影响因子：
2.1
通讯作者：
Kim, Kwan-Suk
中科院分区：
文献类型：
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作者：
Dadi, Hailu;Lee, Seung-Hwan;Kim, Kwan-Suk
为了促进韩国正在进行的牛保护和改良计划，我们研究了东亚牛之间的遗传关系，重点是韩国本土牛，使用完整的线粒体DNA控制区序列。在东亚牛中，总共有67个单倍型被97个可变位点区分。在这些变异位点中，35个为单变异位点，62个为简约信息位点。对于韩国牛，30个单倍型由40个可变位点区分。本研究中鉴定的可变位点对应于转换或颠换点突变。东亚牛群体间遗传距离为0.004 ~ 0.052。在韩国褐和济州黑之间观察到的遗传差异（0.004）是最低的。蒙古牛与其他研究的东亚牛种群略有不同。网络分析发现，济州黑和云边样本代表可能的祖先单倍型T3牛主血统。因此，我们假设济州和云边牛可能代表了该地区原始的东北亚牛。
In order to facilitate the on-going cattle conservation and improvement programs in Korea, we examined genetic relationships among East Asian cattle, focusing on Korean native cattle, using complete mitochondrial DNA control region sequences. In total, 67 haplotypes were discriminated by 97 variable sites in East Asian cattle. Of the variable sites, 35 represented singleton variable sites and 62 were parsimony informative sites. For Korean cattle, 30 haplotypes were discriminated by 40 variable sites. The variable sites identified in this study correspond to transition or transversion point mutations. Inter-populations genetic distance varied from 0.004 to 0.052 for East Asian cattle populations. The genetic divergence observed between Korean Brown and Jeju Black (0.004) was among the lowest. The Mongolian cattle were slightly divergent from other East Asian cattle populations studied. The network analysis uncovered that Jeju Black and Yunbian samples represented the possible ancestral Haplotype within T3 Bos taurus main lineage. Thus, we hypothesized that the Jeju and Yunbian cattle may represent one of the original native North East Asian cattle in the region.