Microbial findings at failing implants
Microbial findings at failing implants
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DOI：
10.1034/j.1600-0501.1999.100501.x
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发表时间：
1999-10-01
影响因子：
4.3
通讯作者：
Dahlén, G
中科院分区：
文献类型：
--
作者：
Leonhardt, Å;Renvert, S;Dahlén, G
这项研究的目的是评估钛种植体与健康组织包围的种植体相比，在临床和放射学上表现出支持组织丢失(种植体周围炎)的临床和放射学迹象时，种植体龈下微生物区系的质量差异。37例种植体骨丢失大于或等于3根、探查出血和/或化脓性出血的患者和51例临床健康且无骨丢失的患者被纳入研究。在每个患者中，使用纸尖获取龈下细菌样本，并通过培养进行微生物分析。这两种类型的临床情况显示出不同的细菌图谱。种植体周炎牙周病原菌有牙龈卟啉单胞菌、中间普雷沃特氏菌和放线杆菌的病例占60%，与牙周炎无关的微生物有葡萄球菌、肠杆菌和念珠菌占55%。相比之下，被健康组织包围的种植体显示出与牙周健康相关的微生物区系。结果表明，健康种植体周沟的微生物区系与相应牙周条件下的微生物区系相似。然而，在种植体周围区域，葡萄球菌？肠道细菌和酵母菌的发现频率几乎与周围病原菌相同，这表明与牙周炎影响牙齿周围的微生物区系相比有所不同。因此，微生物学诊断可能对种植体周围感染患者选择抗菌治疗具有指导意义。
The aim of this study was to evaluate qualitative differences in the subgingival microbiota at titanium implants, ad modum Branemark, demonstrating clinical and radiographic signs of loss of supporting tissues (peri-implantitis) as compared to implants surrounded by healthy tissues. A total of 37 patients demonstrating 1 or more implants with bone loss greater than or equal to 3 threads, bleeding on probing and/or suppuration and 51 patients with clinically healthy mucosa and no bone loss were recruited for the study. In each patient subgingival bacterial samples were obtained using paper-points, and subjected to microbiological analysis by culture. The two types of clinical conditions showed distinct bacterial profiles. For implants with peri-implantitis putative periodontal pathogens, such as Porphyromonas gingivalis, Prevotella intermedial Prevotella nigrescens and Actinobacillus actinomycetemocomitans, were found in 60% of the cases and microorganisms primarily not associated with periodontitis, such as Staphylococcus spp., enterics and Candida spp., were found in 55% of the peri-implant lesions. In contrast, implants surrounded by healthy tissue demonstrated a microbiota associated with periodontal health. The results indicate that the microbiota of the healthy peri-implant sulci is similar to that from corresponding conditions around teeth. However, in peri-implant areas staphylococci? enterics and yeasts were found almost as frequently as periopathogens indicating differences as compared to the microbiota around periodontitis affected teeth. A microbiological diagnosis may therefore be of guidance for the choice of antimicrobial treatment in patients with peri-implant infection.