Clinical curative effect of electric acupuncture on acute cerebral infarction: a randomized controlled multicenter trial
Clinical curative effect of electric acupuncture on acute cerebral infarction: a randomized controlled multicenter trial
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DOI：
10.1016/s0254-6272(15)30075-3
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发表时间：
2014-12-15
影响因子：
2.6
通讯作者：
Wang, Zhuxing
中科院分区：
文献类型：
--
作者：
Wang, Chengwei;Wu, Zhongchao;Wang, Zhuxing
目的：探讨电针能否改善缺血性中风急性期患者的日常生活能力。方法：采用分层随机对照多中心试验设计。将340例急性缺血性中风患者随机分为电针组和对照组。电针组170例采用电针配合常规治疗，对照组170例仅采用常规治疗。评价疗效的主要指标为随访3个月和6个月时的Barthel指数和再住院人数。评定疗效的次要指标是随访4周和12周神经功能障碍评分的变化，以及随访期间坚持针灸康复治疗的患者数量。结果：两组病例选择时的基线数据相似。与对照组比较，电针组6个月随访的优势比(OR)为0.92，致残率的95%可信区间(G)为0.49~1.73，再住院率的OR为0.73和0.51~1.05。两组在12周随访结束时神经功能障碍评分无差异。治疗4周末，电针组神经功能障碍评分明显高于对照组(P
OBJECTIVE: To examine whether electric acupuncture can improve the daily life of patients with ischemic cerebral apoplexy at acute stage.METHODS: A stratified-block randomized controlled multicenter trial was designed for this study. Totally 340 patients with acute ischemic cerebral apoplexy were randomly divided into an electric acupuncture group and a control group. In the electric acupuncture group, 170 patients were treated with electric acupuncture and routine therapy, and 170 patients in the control group with routine therapy alone. Major indexes for judging curative effect were Barthel index at 3-and 6-months follow-up visits and number of re-hospitalized patients. Minor indexes for judging curative effect were change in the score for nervous dysfunction at 4 and 12 weeks follow-up visits and number of patients persisting in rehabilitation treatment with acupuncture during follow-up visit.RESULTS: Baseline data at the time of case selection between the two groups were similar. The odds ratio (OR) was 0.92, and the 95% confidence interval (G) was 0.49-1.73 in disabled rate and 0.73 and 0.51-1.05 in the number of re-hospitalized patients in the electric acupuncture group at 6-month follow up visit compared with the control group. There was no difference in the score for nervous dysfunction at the end of 12-week follow-up visit between the two groups. The score for nervous dysfunction at the end of 4-week treatment in the electric acupuncture group was significantly higher than that in the control group (P