An Australian Aboriginal birth cohort: a unique resource for a life course study of an Indigenous population. A study protocol.
An Australian Aboriginal birth cohort: a unique resource for a life course study of an Indigenous population. A study protocol.
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DOI：
10.1186/1472-698x-3-1
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发表时间：
2003-03-06
影响因子：
3
通讯作者：
Reid, Alison
中科院分区：
文献类型：
--
作者：
Sayers, Susan M;Mackerras, Dorothy;Reid, Alison
背景：全球2型糖尿病及其并发症的增加引起了人们对非传染性疾病对正在进行流行病学转变的人群的负担的关注。出生队列的生命过程方法有可能增加我们对这些慢性疾病发展的了解。1987年，我们试图建立一个澳大利亚土著出生队列，作为特别关注非传染性疾病的描述性和分析性研究的资源。本报告的重点是招募和跟踪居住在澳大利亚北领地顶端人烟稀少的大片地区的不同文化和语言群体的原住民出生的流动对象队列。方法：对1987-1990年在皇家达尔文医院出生的原住民独生子女进行前瞻性纵向研究，对受试者1998-2001年在70多个不同地点进行第二波横断面随访检查。采用多阶段方案对686名城市和农村儿童不同方法的受试者进行定位和数据收集。使用了手工图表审计、向偏远社区发送传真、死亡登记处和具有土著社区过去经验的全职主题定位器。讨论：14年后，对686名土著受试者的成功招募进行了跟踪，确定了95%的受试者的生命状态，并对86%的受试者进行了检查，表明可以在地理、文化和气候挑战的环境中建立土著出生队列。招募和随访率高表明，在支持性人群中有有效的后续战略。
BACKGROUND: The global rise of Type 2 diabetes and its complications has drawn attention to the burden of non-communicable diseases on populations undergoing epidemiological transition. The life course approach of a birth cohort has the potential to increase our understanding of the development of these chronic diseases. In 1987 we sought to establish an Australian Indigenous birth cohort to be used as a resource for descriptive and analytical studies with particular attention on non-communicable diseases. The focus of this report is the methodology of recruiting and following-up an Aboriginal birth cohort of mobile subjects belonging to diverse cultural and language groups living in a large sparsely populated area in the Top End of the Northern Territory of Australia. METHODS: A prospective longitudinal study of Aboriginal singletons born at the Royal Darwin Hospital 1987-1990, with second wave cross-sectional follow-up examination of subjects 1998-2001 in over 70 different locations. A multiphase protocol was used to locate and collect data on 686 subjects with different approaches for urban and rural children. Manual chart audits, faxes to remote communities, death registries and a full time subject locator with past experience of Aboriginal communities were all used. DISCUSSION: The successful recruitment of 686 Indigenous subjects followed up 14 years later with vital status determined for 95% of subjects and examination of 86% shows an Indigenous birth cohort can be established in an environment with geographic, cultural and climatic challenges. The high rates of recruitment and follow up indicate there were effective strategies of follow-up in a supportive population.