Cadmium-induced stimulation of stress-protein hsp70 in lichen photobiont Trebouxia erici
Cadmium-induced stimulation of stress-protein hsp70 in lichen photobiont Trebouxia erici
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DOI：
10.1007/s10725-006-9112-8
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发表时间：
2006-11-01
影响因子：
4.2
通讯作者：
Solar, Peter
中科院分区：
文献类型：
--
作者：
Backor, Martin;Gibalova, Antonia;Solar, Peter
研究了短期暴露于镉和铜（0.0、1.0、5.0 和 10.0 μM）时地衣光生物体 Trebouxia erici 中应激蛋白 70 (hsp70) 的表达。由于蛋白质稳态的维持，我们在未经处理的细胞和经重金属处理的细胞中发现了两种 hsp70 亚型。铜处理的细胞在所有测试浓度下都具有相对恒定的 hsp70 量。然而，Cd 导致 hsp70 表达增加，尤其是在最低浓度（1.0 μM）下。较高的 Cd 浓度与急性毒性和细胞中 hsp70 表达的减少有关。
The expression of stress protein 70 (hsp70) was studied in lichen photobiont Trebouxia erici during short-term exposition to cadmium and copper (0.0, 1.0, 5.0 and 10.0 mu M). We found two isoforms of hsp70 in the untreated as well as in heavy metal-treated cells due to the maintenance of protein homeostasis. Cu-treated cells had a relatively constant amount of hsp70 over all the tested concentrations. However, Cd caused an increase in hsp70 expression, especially at the lowest concentration (1.0 mu M). Higher Cd concentrations were associated with acute toxicity and a reduced expression of hsp70 in the cells.