Kikuchi's disease, skin and systemic lupus erythematosus
Kikuchi's disease, skin and systemic lupus erythematosus
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菊池氏病、皮肤和系统性红斑狼疮
DOI：
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发表时间：
2002
影响因子：
10.3
通讯作者：
A. Kanwar
中科院分区：
文献类型：
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作者：
S. Kaur;G. Thami;A. Kanwar
先生，我们报告了一名原本健康的44岁女性，她抱怨鼻背右侧镜框下方有一处持续3个月的孤立性病变。临床诊断为毛细血管瘤后行切除活检。用于组织病理学检查的福尔马林®固定的组织尺寸为8 <$4 <$2 mm。活检标本上未见肉眼可见病变。组织学检查显示真皮内有一个局限性和超腔定位的肿瘤性血管病变，由扩张的血管间隙组成，偶尔有腔内基质乳头状突起。非树枝状狭窄血管结构切割胶原蛋白，并有逐渐消失到网状真皮中的趋势（图1，2）。这些肿瘤性血管间隙内衬着饱满的内皮细胞，细胞质稀少，细胞核大，表现出嗜甲细胞形态学，这在血管上尤其突出（图3）。血管腔内含有少量
SIR, We report an otherwise healthy 44-year-old woman complaining of a solitary lesion of 3 months' duration, located on the right side of the nasal dorsum underneath the frame of her spectacles. Excisional biopsy was performed with the clinical diagnosis of capillary haemangioma. The formalin-®xed tissue received for histopathological examination was 8 ́ 4 ́ 2 mm in size. No gross lesion was visible on the biopsy specimen. Histology revealed a circumscribed and super®cially located neoplastic vascular lesion within the dermis consisting of dilated vascular spaces with occasional endoluminal stromal papillary projections. The non-arborizing narrow vascular structures dissected the collagen with a tendency to progressively disappear into the reticular dermis (Figs 1,2). These neoplastic vascular spaces were lined by plump endothelial cells with scant cytoplasm and large nuclei exhibiting ÔhobnailÕ cytomorphology, which was particularly prominent in the super®cial vessels (Fig. 3). Vascular lumina contained a small number