The Importance of Knowing When You Don't Remember: Neural Signaling of Retrieval Failure Predicts Memory Improvement Over Time
The Importance of Knowing When You Don't Remember: Neural Signaling of Retrieval Failure Predicts Memory Improvement Over Time
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DOI：
10.1093/cercor/bhw352
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发表时间：
2018-01-01
期刊：
影响因子：
3.7
通讯作者：
Ghetti, Simona
中科院分区：
文献类型：
--
作者：
Fandakova, Yana;Bunge, Silvia A.;Ghetti, Simona
正如记住先前事件的能力对指导我们的决策至关重要一样，认识到我们记忆的局限性的能力也是如此。事实上，我们假设，随着时间的推移，提取失败的神经信号促进了更准确的记忆判断。为了验证这一假设，我们收集了8至9奥尔兹，10至12奥尔兹和成人的纵向功能磁共振成像数据，两个时间点间隔约1.4年（共198次扫描）。参与者进行了一项情景记忆提取任务，他们可以选择一个响应或报告有关目标记忆细节的不确定性。在不准确或不确定的反应过程中，前额叶皮层活动更强烈的儿童表现出更大的纵向增加，以决定报告不确定性;这两个神经变量预测情节记忆的改善。总之，这些结果表明，支持有效认知控制和决策的大脑过程在童年中期继续发展，并在记忆发展中发挥重要作用。
Just as the ability to remember prior events is critical for guiding our decision-making, so too is the ability to recognize the limitations of our memory. Indeed, we hypothesize that neural signaling of retrieval failure promotes more accurate memory judgments over time. To test this hypothesis, we collected longitudinal functional magnetic resonance imaging data from 8 to 9 years olds, 10 to 12 years olds, and adults, with two time points spaced approximately 1.4 years apart (198 scan sessions in total). Participants performed an episodic memory retrieval task in which they could either select a response or report uncertainty about the target memory detail. Children who engaged anterior insula more strongly during inaccurate or uncertain responses exhibited greater longitudinal increases in anterior prefrontal cortex activation for decisions to report uncertainty; both of these neural variables predicted improvements in episodic memory. Together, the results suggest that the brain processes supporting effective cognitive control and decision-making continue to develop in middle childhood and play an important role for memory development.