Relations of Radial Vibration of the Arterial Wall to Pulsatile Parameters in Blood Flow for Extraction of Arterial Indices
Relations of Radial Vibration of the Arterial Wall to Pulsatile Parameters in Blood Flow for Extraction of Arterial Indices
复制标题
动脉壁径向振动与血流脉动参数的关系用于提取动脉指数
DOI：
10.1115/1.4055390
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Hao, Zhili
中科院分区：
文献类型：
--
作者：
Hao, Zhili
鉴于动脉壁径向振动具有广泛的临床应用价值，本文对动脉壁径向振动与血流脉动参数的关系进行了理论研究。将脉搏波在动脉中的传播表示为血流和动脉壁的控制方程以及血-壁界面处无滑移条件的组合，分析得到了脉搏波的波速以及脉动压表示的血流率和径向壁位移量的理论表达式。利用脉搏信号的谐波，推导了无反射和有反射两种情况下动脉壁径向振动与血流脉动参数的理论关系式。这些理论关系确定了简化关系在动脉壁径向振动的应用中的假设，具有临床价值。将动脉壁视为单位质量振动系统，利用这些简化关系从动脉壁的径向振动中提取动脉指数。讨论了这种关系的其他临床应用价值，并从能量和一维波动方程的角度进一步揭示了动脉壁和血流之间的相互作用。在考虑了谐波和波反射的情况下，推导出的径向壁振动和血流脉动参数的理论表达式以及它们之间的关系，为更好地解释其临床价值提供了理论指导，并明确了生理含义和假设。
Given the wide utility of radial vibration of the arterial wall for clinical values, this paper presents a theoretical study on the relations of radial vibration of the arterial wall to pulsatile parameters in blood flow. Pulse wave propagation in an artery is formulated as a combination of the governing equations of blood flow and the arterial wall and no-slip conditions at the blood-wall interface and is analyzed to obtain the wave velocity and the theoretical expressions for blood flow rate and radial wall displacement in terms of pulsatile pressure. With the harmonics of a pulse signal, theoretical relations of radial vibration of the arterial wall to pulsatile parameters in blood flow are derived under two conditions: without and with wave reflection. These theoretical relations identify the assumptions for the simplified relations employed in the utility of radial vibration of the arterial wall for clinical values. With the arterial wall treated as a unit-mass vibration system, these simplified relations are utilized for extraction of arterial indices from radial vibration of the arterial wall. Other applications of such relations for clinical values are discussed, and the interaction between the arterial wall and blood flow is further revealed from the perspective of energy and one-dimensional wave equations. With harmonics and wave reflection considered, the derived theoretical expressions for radial wall vibration, pulsatile parameters in blood flow, and the relations between them provide theoretical guidance for improving their interpretation of clinical values with clearly defined physiological implications and assumptions.