Development of bioadhesives from marine mussels
Development of bioadhesives from marine mussels
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DOI：
10.1002/biot.200700258
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发表时间：
2008-05-01
影响因子：
4.7
通讯作者：
Lim, Seonghye
中科院分区：
文献类型：
--
作者：
Cho, Hyung Joon;Hwang, Dong Soo;Lim, Seonghye
贻贝粘附蛋白由于其优异的生物相容性、对各种材料的粘附性、水置换性、对人体无害性和可控的生物降解性等特性，作为潜在的生物医学和环境友好型水下粘合剂受到越来越多的关注。从贻贝中鉴定出了多种贻贝粘附蛋白，并对其进行了表征，积累了关于贻贝粘附的深入的生物化学知识。此外，人们已经投入了大量的努力来实现这些来自海洋贻贝的生物粘附材料的前景。在这里，在不同的发展途径，特别强调贻贝粘附蛋白的功能性生产的进展，进行了审查。
Mussel adhesive proteins have received increased attention as potential biomedical and environmentally friendly underwater adhesives thanks to their fascinating properties, including strong and flexible adhesion, adhesion to various material substrates, water displacement, that they are harmless to human body, and controlled biodegradability. Several mussel adhesive proteins have been identified and characterized from mussels, and profound biochemical knowledge for mussel adhesions has been accumulated. In addition, a lot of effort has been put into realizing the promise of these bioadhesive materials from marine mussels. Here, progress in the diverse developmental approaches, with particular emphasis on functional production of mussel adhesive proteins, are reviewed.