Treatment of cognitive impairment in multiple sclerosis.

Treatment of cognitive impairment in multiple sclerosis.
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DOI:
10.1155/2006/545860
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发表时间:
2006
影响因子:
2.8
通讯作者:
Griffith N
Griffith N
中科院分区:
医学3区
文献类型:
--
作者:
Pierson SH;Griffith N

文献摘要

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多发性硬化症的认知障碍是一个日益被认识的实体。本文综述了多发性硬化症的认知损害、其患病率、与不同类型多发性硬化症的关系以及对长期功能预后的贡献。讨论还集中在多发性硬化症认知功能障碍的关键因素上,这些因素将多发性硬化症与其他形式的认知障碍区分开来。综述了可能对多发性硬化症认知损害有效的治疗干预措施,包括疾病调整疗法的效果以及物理和认知干预措施的使用。
Cognitive impairment in multiple sclerosis is an increasingly recognized entity. This article reviews the cognitive impairment of multiple sclerosis, its prevalence, its relationship to different types of multiple sclerosis, and its contribution to long-term functional prognosis. The discussion also focuses on the key elements of cognitive dysfunction in multiple sclerosis which distinguish it from other forms of cognitive impairment. Therapeutic interventions potentially effective for the cognitive impairment of multiple sclerosis are reviewed including the effects of disease modifying therapies and the use of physical and cognitive interventions.