Identifying fetal alcohol spectrum disorder among South African children at aged 1 and 5 years.
Identifying fetal alcohol spectrum disorder among South African children at aged 1 and 5 years.
复制标题
DOI：
10.1016/j.drugalcdep.2020.108266
复制
发表时间：
2020-12-01
影响因子：
4.2
通讯作者：
Tomlinson M
中科院分区：
文献类型：
--
作者：
Wynn A;Rotheram-Borus MJ;Davis E;le Roux I;Almirol E;O'Connor M;Tomlinson M
Fetal Alcohol Spectrum Disorders (FASD) are a global health concern. Early intervention mitigates deficits, yet early diagnosis remains challenging. We examine whether children can be screened and meet diagnoses for FASD at 1.5 years compared to 5 years post-birth. A population cohort of pregnant women in 24 neighborhoods (N=1258) was recruited and 84.5%−96% were reassessed at two weeks post-birth, 0.5 years, 1.5 years, 3 years, and 5 years later. A two-step process was followed to diagnose FASD; first, a paraprofessional screened the children and then a physician evaluated the child. Logistic regression models examined differences in children receiving a positive FASD screening (n=160) at 1.5 years vs. 5 years and maternal predictors of the FASD positive screening and diagnosis. Screening positive for FASD more than doubled from 1.5 years to 5 years (from 6.8% to 14.8%). About one quarter of children who screened positive and were evaluated by a physician, were diagnosed as having a FASD. However, half did not complete second stage screening. Mothers without Stage 2 screening were more likely to live in informal housing than those who did (81.3% vs. 62.5%, p=0.014). We found that children can be screened and diagnosed for FASD at 1.5 and 5 years. As FASD characteristics develop over time, repeated screenings are necessary to identify all affected children and launch preventive interventions. Referrals for children to see a physician to confirm diagnosis and link children to care remains a challenge. Integration with the primary healthcare system might mitigate some of those difficulties.
登录
查看更多内容
DOI：
10.1097/dbp.0b013e3182905587
发表时间：
2013-06
期刊：
Journal of developmental and behavioral pediatrics : JDBP
影响因子：
--
作者：
May PA;Tabachnick BG;Gossage JP;Kalberg WO;Marais AS;Robinson LK;Manning MA;Blankenship J;Buckley D;Hoyme HE;Adnams CM
通讯作者：
Adnams CM
影响因子：
--
作者：
Bush, K;Kivlahan, DR;Bradley, KA
通讯作者：
Bradley, KA
影响因子：
5.4
作者：
O'Connor, Mary J.;Tomlinson, Mark;Rotheram-Borus, Mary Jane
通讯作者：
Rotheram-Borus, Mary Jane
影响因子：
3.6
作者：
Lange, Shannon;Rovet, Joanne;Popova, Svetlana
通讯作者：
Popova, Svetlana
影响因子：
2.9
作者：
Burd, L;Cotsonas-Hassler, TM;Kerbeshian, J
通讯作者：
Kerbeshian, J