Mitochondrial DNA variation of Tai speaking peoples in northern Thailand
Mitochondrial DNA variation of Tai speaking peoples in northern Thailand
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DOI：
10.2306/scienceasia1513-1874.2007.33.443
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发表时间：
2007-12-01
期刊：
影响因子：
1.2
通讯作者：
Kangwanpong, Daoroong
中科院分区：
文献类型：
--
作者：
Kampuansai, Jatupol;Bertorelle, Giorgio;Kangwanpong, Daoroong
泰国北部泰族人群的遗传结构和遗传亲缘关系从未被调查过，因此他们的生物祖先和他们的历史没有得到明确的解决。在这项研究中，我们检测了来自4元、4卢、1勇和1坤10个村庄的4个泰族496名无亲缘关系个体的线粒体DNA d环片段。通过16048 ~ 16569位522 bp序列的比较，鉴定出了由130个多态性位点定义的195个不同的单倍型。其中，154种是各自种群所特有的，41种是两个或两个以上种群共有的。所研究的泰人种群显示出人口扩张的证据，相应的估计扩张时间比现在早66000多年。在历史迁移和定居过程中，密集的遗传漂变和奠基人效应在种群分化中留下了印记。群体间的遗传亲缘关系与其语言分类并不一致。泰国北部的元族或孔曼族与中国南部和东南部的泰族关系密切，这支持了移民假说和他们的祖先起源。然而，需要对Khon Muang与泰国北部长期存在的人口Lawa和Mon之间的混合进行调查。
The genetic Structure and genetic affinity of Tai ethnic populations in northern Thailand has never been investigated, therefore their biological ancestor as well as their history is not clearly resolved. In this study, we examined the D-loop fragment of the mitochondrial DNA in 496 unrelated individuals belonging to 4 Tai ethnic groups from 10 villages: 4 Yuan, 4 Lue, 1 Yong and 1 Khuen. Based on a comparison of 522-bp sequences at the position 16048-16569, 195 distinct haplotypes defined by 130 polymorphic sites were distinguished. Of these, 154 types were unique to their respective populations, whereas 41 were shared by two or more populations. The studied Tai populations showed evidence of demographic expansion with corresponding estimated expansion times of more than 66,000 years before the present. During historical migration and settlement, intensive genetic drift and founder effects left their imprint as population differentiation. Genetic affinity among the populations was not consistent with their linguistic classification. The Yuan or Khon Muang in northern Thailand exhibited a close relationship to the Tai groups in South and Southeast China, which supported the immigrant hypothesis and their ancestor's origin. However, an admixture between the Khon Muang and the Lawa and Mon, the long existing populations of northern Thailand, needs to be investigated.