Insulin sensitivity is increased and fat oxidation after a high-fat meal is reduced in normal-weight healthy men with strong familial predisposition to overweight.

Insulin sensitivity is increased and fat oxidation after a high-fat meal is reduced in normal-weight healthy men with strong familial predisposition to overweight.
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DOI：
10.1038/sj.ijo.0802589
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发表时间：
2004-02-01
期刊：
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity
影响因子：
--
通讯作者：
Riccardi, G
Riccardi, G
中科院分区：
其他
文献类型：
--
作者：
Giacco, R;Clemente, G;Riccardi, G

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目的：评价有肥胖家族史、肥胖高危人群的健康、正常体重受试者是否存在餐后能量消耗和/或脂质氧化异常。设计：病例对照研究。8名受试者的父母都超重(父亲和母亲的体重指数(BMI)和25公斤/米(2))，8名受试者的父母体重正常(父亲和母亲的BMI
OBJECTIVE: To evaluate whether postprandial abnormalities of energy expenditure and/or lipid oxidation are present in healthy, normal-weight subjects with a strong family history of obesity and thus at high risk to become obese.DESIGN: Case-control study.SUBJECTS: A total of 16 young healthy men participated in the study. Eight subjects had both parents overweight (father's and mother's body mass index (BMI) >25 kg/m(2)) and eight had both parents with normal body weight (father's and mother's BMI