Is midtrimester short cervix a sign of intraamniotic inflammation?
Is midtrimester short cervix a sign of intraamniotic inflammation?
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DOI：
10.1016/j.ajog.2009.01.047
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发表时间：
2009-04-01
影响因子：
9.8
通讯作者：
Hanna, Nazeeh
中科院分区：
文献类型：
--
作者：
Kiefer, Daniel G.;Keeler, Sean M.;Hanna, Nazeeh
目的：探讨中期短子宫颈患者宫颈短缩程度与羊膜炎症的关系。研究设计：对16-24周的单胎妊娠进行羊膜穿刺术，超声宫颈长度(CL)为1500 pg/mL，CL为5 mm时，预测MCP-1水平升高的敏感性为86%，特异性为85%，阳性预测值为58%，阴性预测值为96%。排除羊水内感染或分娩的患者后，结果相似。
OBJECTIVE: We sought to determine the relationship between the degree of cervical shortening and intraamniotic inflammation in patients presenting with a midtrimester short cervix.STUDY DESIGN: Amniocentesis was performed on singleton pregnancies between 16-24 weeks' gestation with a sonographic cervical length (CL) 1500 pg/mL, CL of 5 mm had an 86% sensitivity, 85% specificity, 58% positive predictive value, and 96% negative predictive value to predict elevated MCP-1 levels. After excluding patients with intraamniotic infection or labor, findings were similar.CONCLUSION: CL