Occupational risk factors for laryngeal carcinoma: Connecticut, 1975-1980.
Occupational risk factors for laryngeal carcinoma: Connecticut, 1975-1980.
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喉癌的职业危险因素：康涅狄格州，1975-1980 年。
DOI：
10.1093/oxfordjournals.aje.a114371
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发表时间：
1986
影响因子：
5
通讯作者：
Walter,SD
中科院分区：
文献类型：
--
作者：
Zagraniski,RT;Kelsey,JL;Walter,SD
一项关于康涅狄格州纽黑文市白色男性喉癌可能的职业危险因素的病例对照研究，包括1975年至1980年诊断的92例病例和181例医院对照，这些病例在年龄、入院年份和医院、居住县、吸烟状况（当前与既往吸烟者）和入院时使用的烟草类型方面单独匹配。仅纳入研究时存活的病例和对照。在条件线性逻辑模型中控制烟草和酒精的影响，发现曾从事橡胶制品制造或运输设备制造而不是造船的男性，以及曾从事机械师，调酒师，农民，泥瓦匠或金属磨床的男性的优势比升高。然而，在这些多变量分析中，只有一个职业，机械师，具有统计学显著的优势比（2.5，95%置信区间=1.2-5.2）。砷和镍未被发现是喉癌的危险因素。吸烟量和饮酒量与喉癌风险呈正相关。
A case-control study of possible occupational risk factors for laryngeal carcinoma in white males in the New Haven, Connecticut, area included 92 cases diagnosed between 1975 and 1980 and 181 hospital controls individually matched to the cases on age, year and hospital of admission, county of residence, smoking status (current vs. ex-smoker), and type of tobacco used at the time of admission. Only cases and controls who were alive at the time of the study were included. With the effects of tobacco and alcohol controlled in a conditional linear logistic model, elevated odds ratios were found for men who had ever worked in rubber products manufacturing or transportation equipment manufacturing other than shipbuilding, and for men who had ever been machinists, bartenders, farmers, masons, or metal grinders. However, only one occupation, machinists, had a statistically significant odds ratio (2.5, 95% confidence interval=1.2–5.2) in these multivariate analyses. Asbestos and nickel were not found to be risk factors for laryngeal carcinoma. Amount of tobacco smoked and alcohol consumed were positively associated with risk for laryngeal cancer.