Building memories: Remembering and forgetting of verbal experiences as predicted by brain activity
Building memories: Remembering and forgetting of verbal experiences as predicted by brain activity
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DOI：
10.1126/science.281.5380.1188
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发表时间：
1998-08-21
期刊：
影响因子：
56.9
通讯作者：
Buckner, RL
中科院分区：
文献类型：
--
作者：
Wagner, AD;Schacter, DL;Buckner, RL
关于人类记忆的一个基本问题是，为什么有些经历会被记住，而另一些则会被遗忘。使用阻塞和事件相关的功能磁共振成像来测量单词编码过程中的大脑激活，以研究神经激活在随后的记忆和随后的遗忘经历中的差异。结果显示，记忆语言经验的能力是由左前额叶和颞叶皮层在该经验中的激活程度预测的。这些发现提供了直接的证据，左前额叶和颞叶区域共同促进可言语事件的记忆形成。
A fundamental question about human memory is why some experiences are remembered whereas others are forgotten. Brain activation during word encoding was measured using blocked and event-related functional magnetic resonance imaging to examine how neural activation differs for subsequently remembered and subsequently forgotten experiences. Results revealed that the ability to later remember a verbal experience is predicted by the magnitude of activation in left prefrontal and temporal cortices during that experience. These findings provide direct evidence that left prefrontal and temporal regions jointly promote memory formation for verbalizable events.