Synaptic transmission at the calyx of Held under in vivo-like activity levels
Synaptic transmission at the calyx of Held under in vivo-like activity levels
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DOI：
10.1152/jn.00355.2007
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发表时间：
2007-08-01
影响因子：
2.5
通讯作者：
Klug, Achim
中科院分区：
文献类型：
--
作者：
Hermann, Joachim;Pecka, Michael;Klug, Achim
体内听觉神经元的特征之一是即使在没有任何感觉刺激的情况下也会发生自发活动。因此，声音诱发的放电爆发就嵌入了这种随机放电的背景中。斜方体内侧核（MNTB）中Held突触的花萼已在体外被表征为快速中继，可以在高刺激频率下可靠地激发（
One of the hallmarks of auditory neurons in vivo is spontaneous activity that occurs even in the absence of any sensory stimuli. Sound-evoked bursts of discharges are thus embedded within this background of random firing. The calyx of Held synapse in the medial nucleus of the trapezoid body (MNTB) has been characterized in vitro as a fast relay that reliably fires at high stimulus frequencies (