Vascular lesions in children: percutaneous MR imaging-guided interstitial Nd:YAG laser therapy--preliminary experience.
Vascular lesions in children: percutaneous MR imaging-guided interstitial Nd:YAG laser therapy--preliminary experience.
复制标题
儿童血管病变：经皮MR成像引导间质Nd:YAG激光治疗——初步经验。
DOI：
10.1148/radiology.208.3.9722861
复制
发表时间：
1998
期刊：
影响因子：
19.7
通讯作者：
K. Wolf
中科院分区：
文献类型：
--
作者：
F. Wacker;D. Cholewa;A. Roggan;A. Schilling;J. Waldschmidt;K. Wolf
目的
探讨使用磁共振（MR）成像指导儿童深部血管瘤和血管畸形的组织间激光治疗。
材料和方法
16名3个月至16岁的有症状的血管病变儿童接受了经皮激光治疗。采用0.2T开放式MR系统进行激光照射器的MR成像引导和在线温度监测。在热疗后2天和6周进行随访研究。
结果
在所有患者中，激光器的交互式定位都是可能的。137个治疗点中有122个（89%）可以进行在线温度监测。术中T1加权图像上的凝固组织体积与随访T2加权图像上的凝固组织体积之间具有良好的相关性。在6周随访时，MR成像显示10例患者的病变尺寸减小（平均减小，72%），2例患者的病变尺寸增加（平均增加，134%）。16例患者中有14例（88%）临床症状改善。
结论
MR成像引导激光治疗对于选定的患有血管病变的儿童来说似乎是一种安全且潜在有效的微创治疗方法。
PURPOSE
To investigate the use of magnetic resonance (MR) imaging to guide interstitial laser therapy of deep hemangiomas and vascular malformations in children.
MATERIALS AND METHODS
Sixteen children aged 3 months to 16 years with symptomatic vascular lesions underwent percutaneous laser treatment. MR imaging guidance of the laser applicator and online thermomonitoring with MR imaging were performed with a 0.2-T open MR system. Follow-up studies were performed 2 days and 6 weeks after thermotherapy.
RESULTS
Interactive positioning of the laser applicator was possible in all patients. Online thermomonitoring was possible in 122 of 137 therapy spots (89%). There was a good correlation between volumes of coagulated tissue on intraprocedural T1-weighted images and volumes of coagulated tissue on follow-up T2-weighted images. At 6-week follow-up, MR imaging demonstrated a reduction in lesion size in 10 patients (mean reduction, 72%) and an increase in lesion size in two patients (mean increase, 134%). Clinical symptoms improved in 14 of 16 patients (88%).
CONCLUSION
MR imaging-guided laser therapy appears to be a safe and potentially effective minimally invasive treatment for selected children with vascular lesions.