Mu rhythm desynchronization is specific to action execution and observation: Evidence from time-frequency and connectivity analysis.
Mu rhythm desynchronization is specific to action execution and observation: Evidence from time-frequency and connectivity analysis.
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DOI：
10.1016/j.neuroimage.2018.09.053
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发表时间：
2019-01-01
期刊：
影响因子：
5.7
通讯作者：
Fox NA
中科院分区：
文献类型：
--
作者：
Debnath R;Salo VC;Buzzell GA;Yoo KH;Fox NA
MU去同步化是脑电能量在阿尔法频率范围内的衰减，记录在中央头皮位置，被认为反映了运动皮质的激活。MU在观察动作时的去同步化被认为反映了人类反射系统的激活。然而，这一概念最近受到了质疑，原因之一是，在观察条件下呈现视觉刺激后，注意过程可能会引起MU节律和枕叶α活动的污染。本研究检验了MU去同步化作为婴儿镜像系统激活的测量方法的有效性，并进一步研究了在执行和观察运动过程中中央和枕区之间的功能连接模式。记录了46名9个月大婴儿执行抓握动作时的脑电，并观察了实验者的抓握动作。将电流源密度(CSD)应用于脑电数据，并对CSD变换后的数据进行时频分析和连通性分析。在执行和观察运动的过程中，中央区域的MU去同步化都很明显。在这两种情况下，枕区也出现了独立的阿尔法去同步化。连通性分析显示，在观察运动时，与大脑其他区域相比，中央枕区在功能上更具连通性。总体而言，这些结果证明了MU去同步化作为婴儿镜像系统活动的指标的有效性，并支持在观察动作时不同的镜像和注意过程之间存在功能联系的提议。
Mu desynchronization is the attenuation of EEG power in the alpha frequency range recorded over central scalp locations thought to reflect motor cortex activation. Mu desynchronization during observation of an action is believed to reflect mirroring system activation in humans. However, this notion has recently been questioned because, among other reasons, the potential contamination of mu rhythm and occipital alpha activity induced by attention processes following presentation of visual stimuli in observation conditions. This study examined the validity of mu desynchronization as a measure of mirroring system activation in infants and further investigated the pattern of functional connectivity between the central and occipital regions during execution and observation of movement. EEG was recorded while 46 9-monthold infants executed grasping actions and observed an experimenter grasping. Current source density (CSD) was applied to EEG data and, time-frequency and connectivity analyses were performed in CSD transformed data. Mu desynchronization was evident over central regions during both execution and observation of movements. Independent alpha desynchronization over occipital region was also present in both conditions. The connectivity analyses revealed that central-occipital areas were functionally more connected compared to other areas of the brain during observation of movements. Collectively, the results demonstrate the validity of mu desynchronization as an index of infant mirroring system activity and support the proposal of a functional connection between distinct mirroring and attention processes during observation of action.
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影响因子：
6.6
作者：
Cuevas, Kimberly;Cannon, Erin N.;Yoo, Kathryn;Fox, Nathan A.
通讯作者：
Fox, Nathan A.
影响因子：
56.9
作者：
Iacoboni, M;Woods, RP;Rizzolatti, G
通讯作者：
Rizzolatti, G
影响因子：
2.1
作者：
Baumgartner, Heidi A.;Oakes, Lisa M.
通讯作者：
Oakes, Lisa M.
DOI：
10.1016/j.cortex.2016.03.019
发表时间：
2016-09
期刊：
Cortex; a journal devoted to the study of the nervous system and behavior
影响因子：
--
作者：
Hobson HM;Bishop DVM
通讯作者：
Bishop DVM
DOI：
10.1073/pnas.0935845100
发表时间：
2003-04-29
影响因子：
11.1
作者：
Carr, L;Iacoboni, M;Lenzi, GL
通讯作者：
Lenzi, GL