Idiopathic bronchiolitis obliterans organizing pneumonia with peripheral infiltrates on chest roentgenogram.
Idiopathic bronchiolitis obliterans organizing pneumonia with peripheral infiltrates on chest roentgenogram.
复制标题
特发性闭塞性细支气管炎组织性肺炎，胸部 X 线照片显示外周浸润。
DOI：
10.1001/archinte.1989.00390020023005
复制
发表时间：
1989
影响因子：
--
通讯作者：
Helen H. Hollingsworth
中科院分区：
文献类型：
--
作者：
T. Bartter;R. Irwin;G. Nash;J. Balikian;Helen H. Hollingsworth
我们报告5例胸部X线片显示与慢性嗜酸性肺炎(CEP)相似的周围性浸润性病变。肺活检标本(经支气管镜和开放肺2例，经支气管镜检查仅3例)均以闭塞性细支气管炎、机化性肺炎(BOOP)为主要表现，2例与CEP消退相一致。我们推测：(1)BOOP可能是常见的外周浸润物，(2)胸片显示外周浸润物不能诊断任何特定的实体，(3)特发性BOOP可能代表未经治疗的CEP的演变，(4)当存在来源不明的外周浸润物时，肺活检可能是比皮质类固醇治疗试验更合适的初始方法，(5)经支气管镜活检可能足以建立有效的临床诊断。
We report five patients with chest roentgenograms showing peripheral infiltrates similar to that described for chronic eosinophilic pneumonia (CEP). While lung biopsy specimens (transbronchial and open in two and transbronchial only in three cases) revealed typical changes of bronchiolitis obliterans organizing pneumonia (BOOP) as the predominant finding in all cases, two cases had changes consistent with a resolving CEP. We speculate that (1) it may be common for BOOP to present with peripheral infiltrates, (2) chest roentgenograms showing peripheral infiltrates are not diagnostic of any specific entity, (3) idiopathic BOOP may represent the evolution of untreated CEP, (4) a lung biopsy may be a more appropriate initial approach than the therapeutic trial of corticosteroids when peripheral infiltrates of unknown origin are present, and (5) transbronchial biopsy may be adequate to establish a working clinical diagnosis of BOOP.