The statistical analysis of treatment effects in 24-hour ambulatory blood pressure recordings.
The statistical analysis of treatment effects in 24-hour ambulatory blood pressure recordings.
复制标题
对24小时动态血压记录的治疗效果进行统计分析。
DOI：
10.1002/sim.4780070608
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发表时间：
1988
影响因子：
2
通讯作者：
Shapiro,AP
中科院分区：
文献类型：
--
作者：
Marler,MR;Jacob,RG;Lehoczky,JP;Shapiro,AP
本文对24小时动态血压记录的治疗效果进行了统计分析。统计模型考虑了昼夜节律、主体效应以及药物或放松疗法的治疗效果。考虑到受试者的异质性，我们对每个受试者的数据拟合了一个单独的线性模型，使用稳健的统计程序来估计线性模型的参数，并在受试者的基础上修剪数据。我们使用元分析方法将研究中所有受试者的结果结合起来。
This paper presents a statistical analysis of treatment effects in 24‐hour ambulatory blood pressure recordings. The statistical models account for circadian rhythms, subject effects, and the effects of treatment with drugs or relaxation therapy. In view of the heterogeneity of the subjects, we fit a separate linear model to the data of each subject, use robust statistical procedures to estimate the parameters of the linear models, and trim the data on a subject by subject basis. We use a meta‐analytical method to combine the results of all subjects in the study.