ANATOMICAL SUBSTRATES OF WOLFF-PARKINSON-WHITE SYNDROME - CLINICOPATHOLOGIC CORRELATION IN 7 PATIENTS
ANATOMICAL SUBSTRATES OF WOLFF-PARKINSON-WHITE SYNDROME - CLINICOPATHOLOGIC CORRELATION IN 7 PATIENTS
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DOI：
10.1161/01.cir.57.5.870
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发表时间：
1978-01-01
期刊：
影响因子：
37.8
通讯作者：
WELLENS, HJJ
中科院分区：
文献类型：
--
作者：
BECKER, AE;ANDERSON, RH;WELLENS, HJJ
对7例已知有心电图显示沃尔夫 - 帕金森 - 怀特综合征证据的患者的心脏进行了临床病理相关性研究。对所有7个心脏的整个房室交界处进行了连续切片。在心电图检查后，预计所有7例都存在房室附加连接。在4个心脏的预测部位通过组织病理学鉴定出连接。在另一例中鉴定出2个连接，其中1个被认为是导致预激的原因。在第6例中，预计存在右侧连接，但组织病理学研究仅发现了结室副纤维。在最后一例中，预测存在后间隔连接，但先前手术后整个间隔已纤维化。根据所使用的研究技术、预激理论以及产生房室附加连接的胚胎发生机制对这些发现进行了讨论。
Clinicopathological correlations were made on the hearts from 7 patients known to have exhibited ECG evidence of the Wolff-Parkinson-White syndrome. In all 7 hearts, the entire atrioventricular junctions were serially sectioned. Accessory atrioventricular connections were prediced in all 7 cases following ECG investigation. Connections were identified histopathologically in 4 hearts in the predicted site. In another case 2 connections were identified, 1 being considered responsible for the pre-excitation. In the 6th case a right lateral connection was anticipated, but only accessory nodo-ventricular fibers were identified following histopathologic studies. In the final case, a posterior septal connection was predicted but the entire septum had fibrosed following previous operation. These findings are discussed in the light of the investigative techniques used, the theories of pre-excitation and the embryogenetic mechanisms producing accessory atrioventricular connections.