Recruitment and Retention of Older Adults in Aging Research
Recruitment and Retention of Older Adults in Aging Research
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DOI：
10.1111/j.1532-5415.2008.02015.x
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发表时间：
2008-12-01
影响因子：
6.3
通讯作者：
Studenski, Stephanie
中科院分区：
文献类型：
--
作者：
Mody, Lona;Miller, Douglas K.;Studenski, Stephanie
老年人在临床研究中的代表性仍然不足，尽管他们在美国和世界各地的人口迅速增长。医生经常根据主要涉及年轻，功能更强，更健康的参与者的研究数据为老年人提出治疗计划。在老龄化研究中招募老年人的主要障碍与他们的实质性健康问题、社会和文化障碍以及提供知情同意的能力可能受损有关。机构化的老年人提供了另一层复杂性，需要机构合作参与研究活动。本文提供了研究招募和保留技术和策略，以解决问题，克服障碍，老年人参与临床研究。关键方法包括早期深入规划;最大限度地减少排除标准;确保所有相关方的合作;使用咨询委员会，及时筛查，识别和符合条件的患者的方法;仔细审查获益：风险比以确保其适当;并采用策略以确保在整个护理过程中成功保留。针对感兴趣的条件、部位和人群制定具体的策略，预测潜在的问题，并及时采用预先制定的应急计划，是有效招募和留住人才的关键。
Older adults continue to be underrepresented in clinical research despite their burgeoning population in the United States and worldwide. Physicians often propose treatment plans for older adults based on data from studies involving primarily younger, more-functional, healthier participants. Major barriers to recruitment of older adults in aging research relate to their substantial health problems, social and cultural barriers, and potentially impaired capacity to provide informed consent. Institutionalized older adults offer another layer of complexity that requires cooperation from the institutions to participate in research activities. This paper provides study recruitment and retention techniques and strategies to address concerns and overcome barriers to older adult participation in clinical research. Key approaches include early in-depth planning; minimizing exclusion criteria; securing cooperation from all interested parties; using advisory boards, timely screening, identification, and approach of eligible patients; carefully reviewing the benefit:risk ratio to be sure it is appropriate; and employing strategies to ensure successful retention across the continuum of care. Targeting specific strategies to the condition, site, and population of interest and anticipating potential problems and promptly employing predeveloped contingency plans are keys to effective recruitment and retention.