Is offering post-exposure prevention for sexual exposures to HIV related to sexual risk behavior in gay men?
Is offering post-exposure prevention for sexual exposures to HIV related to sexual risk behavior in gay men?
复制标题
DOI：
10.1097/00002030-200005260-00016
复制
发表时间：
2000-05-26
期刊：
影响因子：
3.8
通讯作者：
Coates, TJ
中科院分区：
文献类型：
--
作者：
Waldo, CR;Stall, RD;Coates, TJ
目的：探讨艾滋病病毒暴露后预防措施(PEP)对男同性恋者性行为危险行为的影响。方法：对旧金山的529名男同性恋者(1998年6月，1999年1月)进行两个横断面样本的面对面街头访谈，评估性危险行为，他们是否听说过暴露后预防措施，以及他们是否知道旧金山有暴露后预防措施。结果：在第一次听说过PEP的人中，24%的人最近有过无保护的肛交，而没有听说过PEP的人中，有26%的人最近有过无保护的肛交。在时间2，那些听说过PEP的人中，37%的人最近进行了无保护的肛交，而没有听说过PEP的人中有26%的人最近从事过无保护的肛交(chi(2)，4.06；P=0.03)。然而，在这两个时间点上，真正知道旧金山有PEP的男性并不比不知道旧金山有PEP的男性报告更多的危险行为。此外，在这两个时间点上，只有一小部分人自我报告PEP具有增加他们的性风险行为的效果。结论：几乎没有证据表明PEP的可用性可能与旧金山男同性恋者更多的性风险有关。然而，PEP对危险行为的潜在影响仍然必须被视为艾滋病毒/艾滋病治疗乐观和男同性恋者危险行为水平可能不断上升的更大背景的一部分。(C)2000年Lippincott Williams&Wilkins。
Objective: To examine the impact of the availability of postexposure prevention (PEP) for sexual exposures to HIV on sexual risk behavior among gay men.Methods: Two cross-sectional samples of 529 gay men in San Francisco (June 1998, January 1999) completed face-to-face street interviews assessing sexual risk behavior and whether they had heard of PEP in general as well as whether they knew that PEP was available in San Francisco. The second sample was collected after a communitywide outreach campaign had been conducted to increase people's knowledge that PEP was available in San Francisco.Results: Of those who had heard of PEP at Time 1, 24% had recently had unprotected anal intercourse, versus 26% of those who had not heard of PEP. At Time 2, 37% of those who had heard of PEP had recently engaged in unprotected anal intercourse versus 26% of those who had not heard of PEP (chi(2), 4.06; P = 0.03). At both time points, however, men who actually knew that PEP was available in San Francisco did not report more risk behavior than men who did not know PEP was available in San Francisco. In addition, only a small percentage at both time points self-reported that PEP had the effect of increasing their sexual risk behavior.Conclusions: There is little evidence that the availability of PEP for sexual exposures may be related to increased sexual risk-taking among gay men in San Francisco. The potential impact of PEP on risk behavior must, however, still be considered as part of the larger context of HIV/AIDS treatment optimism and possibly escalating levels of risk behavior among gay men. (C) 2000 Lippincott Williams & Wilkins.