Reengineering Translational Science: The Time Is Right
Reengineering Translational Science: The Time Is Right
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DOI：
10.1126/scitranslmed.3002747
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发表时间：
2011-07-06
影响因子：
17.1
通讯作者：
Collins, Francis S.
中科院分区：
文献类型：
--
作者：
Collins, Francis S.
尽管在疾病的分子发病机制方面取得了巨大进展，但将基础生物医学研究转化为安全有效的临床应用仍然是一项缓慢、昂贵且容易失败的奋进。为了寻求颠覆性转化创新的机会，美国。S.美国国立卫生研究院（NIH）打算建立一个新的实体，国家推进转化科学中心（NCATS）。NCATS的使命是促进创新方法和技术的产生，这些方法和技术将加强诊断和治疗方法在各种疾病和病症中的开发、测试和实施。新中心的活动将补充，而不是竞争，转化研究正在进行的NIH和其他地方的公共和私营部门。
Despite dramatic advances in the molecular pathogenesis of disease, translation of basic biomedical research into safe and effective clinical applications remains a slow, expensive, and failure-prone endeavor. To pursue opportunities for disruptive translational innovation, the U. S. National Institutes of Health (NIH) intends to establish a new entity, the National Center for Advancing Translational Sciences (NCATS). The mission of NCATS is to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a wide range of diseases and conditions. The new center's activities will complement, and not compete with, translational research being carried out at NIH and elsewhere in the public and private sectors.