Finite-difference time-domain analysis of increased penetration depth in optical coherence tomography by wavefront shaping

Finite-difference time-domain analysis of increased penetration depth in optical coherence tomography by wavefront shaping
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DOI:
10.1364/boe.9.003883
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发表时间:
2018-08-01
影响因子:
3.4
通讯作者:
Shin, Jonghwa
Shin, Jonghwa
中科院分区:
医学2区
文献类型:
--
作者:
Kim, Jong Uk;Choi, Hyun;Shin, Jonghwa

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混浊介质中的多次散射抑制了最佳光聚焦,从而限制了光学相干断层扫描(OCT)的穿透深度。然而,在混浊介质中的多重散射的影响,可以系统地控制通过成形的入射波前。利用麦克斯韦方程组的互易性和时域有限差分数值分析方法,研究了波前整形OCT在理想和实际结构下的极限性能,并与传统方法进行了比较。结果表明,根据OSA开放获取出版协议的条款,优化的撞击波前显著增强了OCT的穿透深度。(C)2018年美国光学学会
Multiple scattering in turbid media inhibits optimal light focusing and thus limits the penetration depth in optical coherence tomography (OCT). However, the effects of multiple scattering in a turbid medium can be systematically controlled by shaping the incident wavefront. The authors utilize the reciprocity of Maxwell's equations and finite-difference time-domain numerical analysis to investigate the ultimate performance bounds of wavefront shaping-OCT under ideal and realistic configurations and compare them with the conventional method. The results reveal that the optimized impinging wavefront significantly enhances the penetration depth of OCT. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement