COMPARATIVE TEST OF METHODS TO DETERMINE PARTICLE-SIZE AND PARTICLE-SIZE DISTRIBUTION IN THE SUBMICRON RANGE
COMPARATIVE TEST OF METHODS TO DETERMINE PARTICLE-SIZE AND PARTICLE-SIZE DISTRIBUTION IN THE SUBMICRON RANGE
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DOI：
10.1002/ppsc.19950120307
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发表时间：
1995-06-01
影响因子：
2.7
通讯作者：
LANGE, H
中科院分区：
文献类型：
--
作者：
LANGE, H
分散体系如胶乳、颜料、陶瓷材料或药物制剂的最重要的特征性质是粒度和粒度分布。为了测量这些量，有几种基于不同物理原理的方法和测量仪器。这些方法包括比浊法、动态和静态光散射法、电子显微镜图像分析法、超离心法和圆盘离心法、光衍射法和电感测区法。所有这些测量技术无疑是必要的，因为产品种类繁多，粒度范围广。然而，如果使用不同的技术，不考虑方法的适用范围和分辨率，不加批判地比较结果，就会出现一些问题。因此，使用具有定义的单峰、双峰和六峰粒度分布的亚微米范围内的七种胶乳进行了广泛的比较试验。测试和比较了测定平均粒度值和粒度分布的最重要方法。在仅测定平均粒径的方法中，比浊法是最有效的，其次是动态光散射累积量评估。静态光散射仅对具有窄粒度分布的小颗粒产生准确的结果。在确定粒度分布的方法中，超离心法和略少的圆盘离心法和带图像分析的电子显微镜法是最有效的。动态光散射仅在具有窄分布曲线的小颗粒的情况下产生可靠的结果。光衍射法和电敏感区法不太适用于亚微米范围。
Among the most important characteristic properties of disperse systems such as latices, pigments, ceramic materials or drug formulations are the particle size and the particle size distribution. To measure these quantities, several methods and measuring instruments based on different physical principles are available. These include tubidimetry, dynamic and static light scattering, electron microscopy with image analysis, ultra- and disc centrifugation, light diffraction and the electrical sensing zone method. All these measuring techniques are doubtless necessary because of the large product variety and the broad particle size range. However, some problems arise if different techniques are used and the results are compared uncritically without considering to the application range and the resolution of the methods. An extensive comparative test was therefore carried out using seven latices in the submicron range with defined monomodal, bimodal and hexamodal particle size distributions. The most important methods of determining average particle size values and particle size distributions were tested and compared. Of the methods to determine only average particle sizes, turbidimetry is the most efficient, followed by dynamic light scattering with cumulants evaluation. Static light scattering only yields accurate results for small particles with narrow particle size distributions, Of the methods to determine particle size distributions, ultracentifugation and, somewhat less, disc centrifugation and electron microscopy with image analysis are the most efficient. Dynamic light scattering only yields reliable results in the case of small particles with narrow distribution curves. Light diffraction and the electrical sensing zone method are less suitable for the submicron range.