THE MONOZYGOTIC TWIN HALF-SIB METHOD FOR ANALYZING MATERNAL EFFECTS AND SEX-LINKAGE IN HUMANS
THE MONOZYGOTIC TWIN HALF-SIB METHOD FOR ANALYZING MATERNAL EFFECTS AND SEX-LINKAGE IN HUMANS
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DOI：
10.1038/hdy.1981.30
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发表时间：
1981-01-01
期刊：
影响因子：
3.8
通讯作者：
LAST, K
中科院分区：
文献类型：
--
作者：
HALEY, CS;JINKS, JL;LAST, K
研究了母体效应和性连锁基因对单卵双胞胎家庭统计数据的影响。如果将后代性别放在一起考虑，母体效应和性别联系可能会被混淆。在没有性别关联的情况下，比较母系和父系半同胞协方差将比传统的母系和父系亲子协方差比较更能检验母系效应。如果将子代性别分开考虑，则性别连锁分析不存在根本问题。
The influence of maternal effects and sex-linked loci upon statistics from an analysis of the families of monozygotic twins is examined. If the progeny sexes are cosidered jointly, maternal effects and sex-linkage may be confused. In the absence of sex-linkage a comparison of maternal and paternal half-sib covariances will be a more powerful test for maternal effects than the conventional comparison of maternal and paternal parent-offspring covariances. If the progeny sexes are considered separately the analysis of sex-linkage presents no fundamental problems.