Pilot Studies to Identify the Optimum Duration of Concomitant Helicobacter pylori Eradication Therapy in Thailand

Pilot Studies to Identify the Optimum Duration of Concomitant Helicobacter pylori Eradication Therapy in Thailand
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确定泰国幽门螺杆菌联合根除治疗最佳持续时间的试点研究

DOI:
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发表时间:
2012
期刊:
影响因子:
4.4
通讯作者:
V. Mahachai
V. Mahachai
中科院分区:
医学2区
文献类型:
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作者:
C. Kongchayanun;R. Vilaichone;Bubpha Pornthisarn;S. Amornsawadwattana;V. Mahachai

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背景和目的:标准三联疗法对幽门螺杆菌感染的 根治率在全球范围内已经下降,包括在泰国,需要新的治疗方案来提供可靠的高根治率。这项研究的目的是确定同时治疗5或10 是否会在感染幽门螺杆菌的泰国非溃疡性消化不良患者中产生95%(A级)的≥ 治疗成功率。
Background and Aim:  Eradication rate for Helicobacter pylori infection with standard triple therapy has globally declined including in Thailand, and new regimens are required that provide reliable high eradication rates. The study was designed to determine whether concomitant therapy administered for either 5 or 10 days would produce a ≥ 95% (grade A) treatment success in H. pylori infected Thai subjects with nonulcer dyspepsia.