Substrate recognition by the 2 micron circle site-specific recombinase: effect of mutations within the symmetry elements of the minimal substrate.
Substrate recognition by the 2 micron circle site-specific recombinase: effect of mutations within the symmetry elements of the minimal substrate.
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2 微米圆位点特异性重组酶的底物识别:最小底物对称元件内突变的影响。
DOI:
10.1128/mcb.6.12.4329-4334.1986
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发表时间:
1986
影响因子:
5.3
通讯作者:
Jayaram,M
中科院分区:
文献类型:
--
作者:
Prasad,PV;Horensky,D;Young,LJ;Jayaram,M
The minimal substrate for the 2µm circle site-specific recombinase FLP consists of a nearly perfect 13-base-pair dyad symmetry with an 8-base-pair core. By using a series of chemically synthesized FLP substrates in in vitro FLP recombination and FLP-binding assays, we have identified four positions within each of the symmetry elements that are important contact points for the FLP protein. Furthermore, the binding and recombination data provide evidence for cooperativity between the two symmetry elements of a substrate and between the symmetry elements of two partner substrates during FLP recombination.
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影响因子:
64.5
作者:
Ross,W;Landy,A
通讯作者:
Landy,A
DOI:
10.1101/sqb.1984.049.01.088
发表时间:
1984
期刊:
Cold Spring Harbor symposia on quantitative biology
影响因子:
--
作者:
M. Mcleod;F. Volkert;J. Broach
通讯作者:
J. Broach
影响因子:
4.8
作者:
D. Babineau;D. Vetter;B. Andrews;R. Gronostajski;G. Proteau;L. Beatty;P. Sadowski
通讯作者:
P. Sadowski
DOI:
10.1016/j.dsx.2019.01.014
发表时间:
2019-03-01
影响因子:
10
作者:
Gateva, Antoaneta T.;Assyov, Yavor S.;Kamenov, Zdravko A.
通讯作者:
Kamenov, Zdravko A.
DOI:
10.1016/0735-0651(84)90001-3
发表时间:
1984
期刊:
Gene Analysis Techniques
影响因子:
--
作者:
A. Seth
通讯作者:
A. Seth