Blood lead levels and growth status among African-American and Hispanic children in Dallas, Texas-1980 and 2002: Dallas Lead Project II
Blood lead levels and growth status among African-American and Hispanic children in Dallas, Texas-1980 and 2002: Dallas Lead Project II
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DOI：
10.1080/03014460902806615
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发表时间：
2009-01-01
影响因子：
1.7
通讯作者：
Gratton, T.
中科院分区：
文献类型：
--
作者：
Little, B. B.;Spalding, S.;Gratton, T.
目的：这项调查的目的是分析儿童血铅水平和生长状况（2-12岁）在达拉斯，得克萨斯州铅冶炼厂社区在20世纪80年代和2002年，冶炼厂从1936年到1990年。方法和材料：在两个队列（n=360）中使用方便研究设计的样本：1980-1989年（n=191）和2002年（n=169）。采用多因素方差分析、协方差分析和串联多元回归分析方法对两个时间段内身高与血铅水平的关系进行了分析。结果如下：2002年儿童平均血铅水平（1.6 g/dL0.2 SE）显著（p 0.001）低于1980年队列平均水平（23.6 g/dL1.3 SE）。2002年的平均身高和体重分别比1980年高4.5厘米和4.0公斤。血铅水平降低与身高、体重和体重指数（BMI）分别增加3.9 cm、3.5 kg和1.1个单位有关。队列效应与较高的身高（0.6 cm）、体重（0.5 kg）和BMI（0.1）相关。结论：这项调查报告了一个社区的儿童在几十年内从高血铅水平过渡到低血铅水平之前和之后的生长情况。以儿童生长为代表，达拉斯铅冶炼厂社区的健康状况在过去二十年中显著增加，主要是因为血铅水平较低，而贫困率仅略低。
Objective: The purpose of this investigation is to analyze childhood blood lead levels and growth status (ages 2-12) in Dallas, Texas lead smelter communities in the 1980s and 2002, where smelters operated from 1936 to 1990. Methods and materials: A sample of convenience study design was used in two cohorts (n=360): 1980-1989 (n=191) and 2002 (n=169). Multivariate analysis of variance and covariance and tandem multiple regressions were used to evaluate the association between stature and blood lead level in two time periods. Results: In 2002 average child blood lead level (1.6 g/dL0.2 SE) was significantly (p0.001) lower compared to the 1980 cohort mean level (23.6 g/dL1.3 SE). Average height and weight in 2002 were 4.5 cm and 4.0 kg greater, respectively, than in 1980. Lowered blood lead level was associated with 3.9 cm, 3.5 kg and 1.1 units greater height, weight and body mass index (BMI), respectively. Cohort effect was associated with greater height (0.6 cm), weight (0.5 kg) and BMI (0.1). Conclusion: This investigation reports on child growth in a community before and after the transition from high to low blood lead levels over several decades. Using child growth as a proxy, health status of Dallas's lead smelter communities increased markedly over the past two decades, primarily because of lower blood lead levels, while the poverty rate was only marginally lower.