Sedation with 50% nitrous oxide/oxygen for outpatient dental treatment in individuals with intellectual disability
Sedation with 50% nitrous oxide/oxygen for outpatient dental treatment in individuals with intellectual disability
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DOI：
10.1111/j.1469-8749.2007.00621.x
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发表时间：
2007-08-01
影响因子：
3.8
通讯作者：
Onody, Peter
中科院分区：
文献类型：
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作者：
Faulks, Denise;Hennequin, Martine;Onody, Peter
智力残疾者难以配合门诊治疗，许多人被转诊接受全身麻醉。智力障碍传统上是清醒镇静的禁忌症。我们评估了行为的影响，有效性和耐受性的镇静在这一人群中使用固定的50%的一氧化二氮/氧气混合物作为一种单一的代理。我们使用牙科治疗作为门诊护理的模型;在7个中心招募了349名患者（192名男性，157名女性;平均年龄22岁[SD 14];范围3- 81岁），为期12个月。如果完成了计划的牙科治疗，则认为镇静成功。采用改良的Venham量表对行为进行评分。在605次会议中，91.4%成功。未发生严重不良反应。轻微不良事件（如恶心）发生在10.1%的会议。我们的结论是，使用安全有效的清醒镇静可能会减少全身麻醉的适应症。
Persons with intellectual disability have difficulty in cooperating with outpatient care, and many are referred for general anaesthesia. Intellectual disability has traditionally been a contraindication for conscious sedation. We evaluated the behavioural impact, effectiveness, and tolerance of sedation in this population using a fixed 50% nitrous oxide/oxygen mixture as a single agent. We used dental treatment as a model of outpatient care; 349 patients (192 males, 157 females; mean age 22y [SD 14]; range 3-81y) were recruited over a 12-month period at seven centres. Sedation was deemed successful if planned dental treatment was completed. Behaviour was scored with the modified Venham scale. Out of 605 sessions, 91.4% were successful. No serious adverse effects occurred. Minor adverse events (such as nausea) occurred in 10.1% of sessions. We conclude that the use of safe and effective conscious sedation may reduce the indications for general anaesthesia.