hypeR: an R package for geneset enrichment workflows
hypeR: an R package for geneset enrichment workflows
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DOI：
10.1093/bioinformatics/btz700
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发表时间：
2020-02-15
期刊：
影响因子：
5.8
通讯作者：
Monti, Stefano
中科院分区：
文献类型：
--
作者：
Federico, Anthony;Monti, Stefano
摘要：基因组富集是一种用于注释高通量测序数据的流行方法。现有的工具无法提供灵活性来解决研究人员在此类分析中面临的各种挑战，特别是在分析多个实验中的许多签名时。我们提出了一个全面的R包，用于generator丰富的工作流程，提供多种丰富，可视化和共享方法，以及分层generator分析和内置的markdown报告等新功能。hypeR是一个一站式的解决方案，可以为广泛的受众和各种用例执行通用程序丰富。
A Summary: Geneset enrichment is a popular method for annotating high-throughput sequencing data. Existing tools fall short in providing the flexibility to tackle the varied challenges researchers face in such analyses, particularly when analyzing many signatures across multiple experiments. We present a comprehensive R package for geneset enrichment workflows that offers multiple enrichment, visualization, and sharing methods in addition to novel features such as hierarchical geneset analysis and built-in markdown reporting. hypeR is a one-stop solution to performing geneset enrichment for a wide audience and range of use cases.