Volumetric Measurement Pulmonary Ground-Glass Opacity Nodules with Multi-detector CT: Effect of Various Tube Current on Measurement Accuracy-A Chest CT Phantom Study
Volumetric Measurement Pulmonary Ground-Glass Opacity Nodules with Multi-detector CT: Effect of Various Tube Current on Measurement Accuracy-A Chest CT Phantom Study
复制标题
DOI：
10.1016/j.acra.2009.02.020
复制
发表时间：
2009-08-01
影响因子：
4.8
通讯作者：
Ma Daqing
中科院分区：
文献类型：
--
作者：
Linning, E.;Ma Daqing
基本原理和目标。本研究的目的是评估各种管电流对使用胸部体模进行磨玻璃样混浊 (GGO) 结节体积测量准确性的影响。材料和方法。使用 64 切片计算机断层扫描仪在不同的管电流（30、60、90、120、150、180 和 210 mA）下扫描包含 13 个已知体积的人造 GGO 结节的胸部模型。使用软件进行体积测量。计算计算机断层扫描体积测量值与参考标准体积之间的相对百分比误差和绝对百分比误差。分析了平均绝对百分比误差与结节平均衰减、固体成分比例与结节平均衰减之间的相关性。结果。相对百分比误差显示，在 30、60 和 90 mA 时，结节体积被严重低估，而在 120、150、180 和 2 10 mA 时，结节体积被大幅高估，但绝对百分比误差没有统计学上的显着差异 (P = .876)。结节体积测量的平均绝对百分比误差与结节平均衰减值的Pearson相关系数呈负相关，结节实性成分占整个结节的比例与结节平均衰减值呈正相关。结论。体积测量是量化 GGO 结节体积的一种有前途的方法。重要的是要知道不同的管电流会影响体积测量的准确性。
Rationale and Objectives. The purpose of this study was to evaluate the effect of various tube currents on the accuracy of volumetric measurements of ground-glass opacity (GGO) nodules using a chest phantom.Materials and Methods. A chest phantom containing 13 artificial GGO nodules with known volumes was scanned using a 64-slice computed tomographic scanner at different tube currents (30, 60, 90, 120, 150, 180, and 210 mA). Volumetric measurements were performed using software. The relative percentage error and the absolute percentage error between the volume measures on computed tomography and the reference-standard volumes were calculated. Correlations between the mean absolute percentage error and the mean attenuation of nodules and between the ratio of solid component and the mean attenuation of nodules were analyzed.Results. The relative percentage errors showed that there was substantial underestimation of nodule volumes at 30, 60, and 90 mA and substantial overestimation of volumes at 120, 150, 180, and 2 10 mA, but there was no statistically significant difference in absolute percentage errors (P = .876). Pearson's correlation coefficient of the mean absolute percentage errors of nodules on volumetric measurement versus the mean attenuation value of nodules showed a negative correlation, and the ratio of solid component to whole nodule versus the mean attenuation of nodules showed a positive correlation.Conclusion. Volume measurement is a promising method for the quantification of GGO nodule volume. It is important to know that different tube currents can affect the accuracy of volumetric measurements.