Specificity of Ertapenem Susceptibility Screening for Detection of Klebsiella pneumoniae Carbapenemases

Specificity of Ertapenem Susceptibility Screening for Detection of Klebsiella pneumoniae Carbapenemases
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DOI:
10.1128/jcm.02143-08
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发表时间:
2009-03-01
影响因子:
9.4
通讯作者:
Edelstein, Paul H.
Edelstein, Paul H.
中科院分区:
医学2区
文献类型:
--
作者:
McGettigan, Shannon E.;Andreacchio, Kathleen;Edelstein, Paul H.

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肺炎克雷伯菌碳青霉烯酶 (KPC) 的检测可能是非特异性的,尤其是当 KPC 不常见时。我们确定了 2,696 株肠杆菌科菌株中厄他培南耐药性 KPC 检测的阳性预测值和特异性。 KPC检测厄他培南耐药的阳性预测值和特异性分别为74%和99.2%。
Detection of Klebsiella pneumoniae carbapenemases (KPCs) can be nonspecific, especially when KPCs are uncommon. We determined the positive predictive value and specificity of ertapenem resistance for KPC detection in 2,696 Enterobacteriaceae isolates. The positive predictive value and specificity of ertapenem resistance for KPC detection were 74% and 99.2%, respectively.