Controlled Generation of 3-Triflyloxyarynes
Controlled Generation of 3-Triflyloxyarynes
复制标题
3-Triflyloxyarynes 的受控生成
DOI：
10.1055/s-0035-1562532
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
and T. Hosoya
中科院分区：
文献类型：
--
作者：
K. Uchida;S. Yoshida;and T. Hosoya
通过1，3-二(三氟氧基)-2-碘代芳烃的碘-镁交换反应，有效地抑制了竞争的Thia-Fries重排反应，有效地生成了3-三氟氧基芳烃，包括那些含有可转化基团的化合物。该方法可以方便地合成多种多取代芳烃。
The efficient generation of 3-triflyloxyarynes, including those bearing a transformable group, through an iodine–magnesium exchange reaction of 1,3-bis(triflyloxy)-2-iodoarenes was achieved by using finely tuned reaction conditions that efficiently suppressed the competing thia-Fries rearrangement. The method enabled the facile synthesis of a wide range of multisubstituted arenes.