Nano-based antiviral coatings to combat viral infections
Nano-based antiviral coatings to combat viral infections
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DOI：
10.1016/j.nanoso.2020.100620
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发表时间：
2020-11-06
影响因子：
--
通讯作者：
Packirisamy G
中科院分区：
文献类型：
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作者：
Basak S;Packirisamy G
最近，病毒感染引起的流行病和大流行病对人类生活产生了巨大影响，导致了严重的社会和财政挑战。其中一个与SARS-CoV-2病毒爆发有关的事件已经在全球范围内夺走了超过917，417条生命（截至2020年9月13日）。病毒的医院传播途径在病毒的社区传播中也发挥着重要作用。不幸的是，现有的策略都不适合预防病毒感染的传播。为了控制病毒传播，主要目标是阻止病毒传播到其他健康的个体。纳米材料由于其独特的物理和化学性质，已被用于开发新型抗病毒药物。在这篇综述中，我们讨论了几种纳米技术的策略，可以用作抗病毒涂层，通过阻止病毒进入宿主细胞来抑制病毒传播。
In the recent past, epidemics and pandemics caused by viral infections have had extraordinary effects on human life, leading to severe social and financial challenges. One such event related to the outbreak of the SARS-CoV-2 virus has already taken more than 917,417 lives globally (as of September 13, 2020). The nosocomial route of viral transmission has also been playing a significant role in the community spreading of viruses. Unfortunately, none of the existing strategies are apt for preventing the spread of viral infections. In order to contain the viral transmission, the principal target would be to stop the virus from reaching the otherwise healthy individuals. Nanomaterials, due to its unique physical and chemical properties, have been used to develop novel antiviral agents. In this review, we have discussed several nanotechnological strategies that can be used as an antiviral coating to inhibit viral transmission by preventing viral entry into the host cells.