Age-specific prevalence of infection with herpes simplex virus types 2 and 1: A global review
Age-specific prevalence of infection with herpes simplex virus types 2 and 1: A global review
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DOI：
10.1086/343739
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发表时间：
2002-10-15
影响因子：
6.4
通讯作者：
Robinson, NJ
中科院分区：
文献类型：
--
作者：
Smith, JS;Robinson, NJ
单纯疱疹病毒（HSV）2型和1型感染的年龄及性别特异性患病率信息对于优化生殖器疱疹控制策略至关重要，随着越来越多的数据表明HSV - 2感染可能会增加人类免疫缺陷病毒的感染和传播，其重要性日益凸显。本综述总结了来自经过同行评审的特异性HSV血清流行病学调查出版物的数据。一般来说，HSV - 2患病率在非洲和美洲最高，在西欧和南欧低于北欧和北美，在亚洲最低。HSV - 2和 - 1的总体患病率以及按年龄划分的患病率因国家、国家内的地区以及人群亚组而有显著差异。特定年龄的HSV - 2患病率通常女性高于男性，在性行为风险较高的人群中也较高。美国的HSV - 2患病率有所上升，但其他国家的全国性数据无法获取。HSV - 1感染在儿童期和青春期获得，其传播范围比HSV - 2感染广泛得多。许多地理区域还需要进一步研究。
Information on age- and sex-specific prevalence of herpes simplex virus (HSV) types 2 and 1 infections is essential to optimize genital herpes control strategies, which increase in importance because accumulating data indicate that HSV-2 infection may increase acquisition and transmission of human immunodeficiency virus. This review summarizes data from peer-reviewed publications of type-specific HSV seroepidemiologic surveys. HSV-2 prevalence is, in general, highest in Africa and the Americas, lower in western and southern Europe than in northern Europe and North America, and lowest in Asia. HSV-2 and -1 prevalence, overall and by age, varies markedly by country, region within country, and population subgroup. Age-specific HSV-2 prevalence is usually higher in women than men and in populations with higher risk sexual behavior. HSV-2 prevalence has increased in the United States but national data from other countries are unavailable. HSV-1 infection is acquired during childhood and adolescence and is markedly more widespread than HSV-2 infection. Further studies are needed in many geographic areas.