Ethical considerations in the interpretation and communication of clinical trial results.
Ethical considerations in the interpretation and communication of clinical trial results.
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DOI：
10.1513/pats.200701-007gc
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发表时间：
2007-05-01
期刊：
影响因子：
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通讯作者：
Coultas, David
中科院分区：
文献类型：
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作者：
Coultas, David
研究结果的伦理解释和交流对于确保患者、医生和监管机构获得新知识的有效性、及时性和可及性至关重要。不遵守伦理原则可能会对患者造成不良后果，因为高估了获益，低估了危害，以及缺乏对获益或危害的及时认识。虽然捏造、伪造和剽窃是研究不端行为的传统标准，但其他更微妙的行为可能会对公共安全和对研究企业的信任造成更大的威胁。在过去的十年中，人们对研究不端行为的认识不断提高，导致世界各地采取了一些举措，试图通过资助机构、研究机构和编辑监督来控制研究过程各个阶段的问题。这篇文章的目的是提高认识的广泛的伦理问题，出现在手稿准备，审查，出版和传播的研究结果，并正在进行的努力，以尽量减少不当行为的肺研究界。
The ethical interpretation and communication of research results is essential to ensure the validity, timeliness, and accessibility of new knowledge for patients, physicians, and regulatory agencies. Failure to adhere to ethical principles may cause adverse outcomes for patients because of overestimation of benefit, underestimation of harm, and lack of timely awareness of benefit or harm. Although fabrication, falsification, and plagiarism are the traditional criteria for research misconduct, other more subtle behaviors may cause greater threats to public safety and trust in the research enterprise. Growing awareness of research misconduct has led to a number of initiatives worldwide during the past decade in an attempt to control the problem at various stages of the research process through the funding agencies, research institutions, and editorial oversight. The objective of this article is to raise awareness among the pulmonary research community of the broad range of ethical issues that arise during manuscript preparation, review, publication, and dissemination of research results, and efforts that are in progress to minimize misconduct.