JPred: a consensus secondary structure prediction server

JPred: a consensus secondary structure prediction server
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DOI:
10.1093/bioinformatics/14.10.892
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发表时间:
1998-01-01
期刊:
影响因子:
5.8
通讯作者:
Barton, GJ
Barton, GJ
中科院分区:
生物学3区
文献类型:
--
作者:
Cuff, JA;Clamp, ME;Barton, GJ

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介绍了一个交互式蛋白质二级结构预测网络服务器。该服务器允许提交单条序列或多重比对序列,并返回六种利用多序列进化信息的二级结构预测算法的预测结果。还会返回一个一致性预测结果,它将预测的平均Q(3)准确率提高了1%,达到72.9%。该服务器简化了当前预测算法的使用,并能够识别对结构和功能重要的保守模式。
An interactive protein secondary structure prediction Internet server is presented. The server allows a single sequence or multiple alignment to be submitted, and returns predictions from six secondary structure prediction algorithms that exploit evolutionary information front multiple sequences. A consensus prediction is also returned which improves the average Q(3) accuracy of prediction by 1% to 72.9%. The server simplifies the use of current prediction algorithms and allows conservation patterns important to structure and function to be identified.