Development of Normal-Suction Boundary Control Method Based on Inflow Cannula Pressure Waveform for the Undulation Pump Ventricular Assist Device
Development of Normal-Suction Boundary Control Method Based on Inflow Cannula Pressure Waveform for the Undulation Pump Ventricular Assist Device
复制标题
波动泵心室辅助装置基于流入插管压力波形的正吸边界控制方法的开发
DOI：
10.1111/j.1525-1594.2012.01451.x
复制
发表时间：
2012
影响因子：
2.4
通讯作者：
and Yusuke Abe
中科院分区：
文献类型：
--
作者：
Kohei Ishii;Itsuro Saito;Takashi Isoyama;Hidemoto Nakagawa;Nakano Emiko;Toshiya Ono;Wei Shi;Yusuke Inoue;and Yusuke Abe
在心室辅助装置（VADs）中，不需要抽吸就能获得最大的辅助。然而，VAD的高驱动功率可能导致严重的心室吸力，导致心律失常、溶血和泵损伤。在本报告中，我们探索了一个合适的VAD驱动水平，在没有严重收缩吸力的情况下最大限度地提高辅助效果。目标驱动电平设置在无吸力低驱动功率与频繁吸力高驱动功率的边界处。在边界范围内，可能会出现间歇性的轻度吸入。驱动功率由吸力的发生来调节。在一只植入了波动泵心室辅助装置（UPVAD）的雌性山羊身上评估了正常吸力边界控制方法。UPVAD驱动为半脉动模式，心跳同步控制。采用为本研究开发的正常吸力边界控制方法调节收缩驱动功率。我们确认驱动功率可以保持在边界范围内。使用吸力比评估吸力的发生情况。我们将这个比率定义为抽吸次数除以心跳次数。当采用正吸边界控制方法时，吸力比降低了70%。
It is desirable to obtain the maximum assist without suction in ventricular assist devices (VADs). However, high driving power of a VAD may cause severe ventricle suction that can induce arrhythmia, hemolysis, and pump damage. In this report, an appropriate VAD driving level that maximizes the assist effect without severe systolic suction was explored. The target driving level was set at the boundary between low driving power without suction and high driving power with frequent suction. In the boundary range, intermittent mild suction may occur. Driving power was regulated by the suction occurrence. The normal‐suction boundary control method was evaluated in a female goat implanted with an undulation pump ventricular assist device (UPVAD). The UPVAD was driven in a semipulsatile mode with heartbeat synchronization control. Systolic driving power was adjusted using a normal‐suction boundary control method developed for this study. We confirmed that driving power could be maintained in the boundary range. Occurrences of suction were evaluated using the suction ratio. We defined this ratio as the number of suction occurrences divided by the number of heartbeats. The suction ratio decreased by 70% when the normal‐suction boundary control method was used.